Double-hit pancreatic B-lymphoblastic lymphoma with a variant translocation t(2;18)(p11;q21)

Double-hit lymphoma is typically categorized as “high-grade B-cell lymphoma, with MYC and BCL2 and/or BCL6 rearrangements”, but in infrequent cases in which terminal deoxynucleotidyl transferase (TdT) expression is positive, it is categorized as B-lymphoblastic lymphoma (B-LBL). BCL2 rearrangements...

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Veröffentlicht in:	International journal of hematology 2019-07, Vol.110 (1), p.107-114
Hauptverfasser:	Yamamoto, Katsuya, Kawamoto, Shinichiro, Kitao, Akihito, Mizutani, Yu, Inui, Yumiko, Yakushijin, Kimikazu, Kajimoto, Kazuyoshi, Hayashi, Yoshitake, Matsuoka, Hiroshi, Minami, Hironobu
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Ascites Ascites cells B-cell lymphoma Bcl-6 protein Beta cells Case Report CD19 antigen Cell proliferation Chromosome banding Chromosomes, Human, Pair 18 - genetics Chromosomes, Human, Pair 2 - genetics Computed tomography DNA nucleotidylexotransferase Fatal Outcome Fatalities Fluorescence Fluorescence in situ hybridization Genes, myc Genetic Variation Heavy chains Hematology Humans Immunoglobulins Lymphoid cells Lymphoma Lymphoma, B-Cell - genetics Male Medicine Medicine & Public Health Myc protein Oncology Pancreas Pancreatic Neoplasms - genetics Pax5 protein Proto-Oncogene Proteins c-bcl-2 - genetics Translocation Translocation, Genetic - genetics
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