Association between PTPN22‐1123G/C and susceptibility to rheumatoid arthritis: A systematic review and meta‐analysis

Background The incidence of rheumatoid arthritis (RA) varies greatly among different ethnic groups, suggesting genetic susceptibility. The several genetic variants of protein tyrosine phosphatase, non‐receptor type 22 (PTPN22‐1123G/C, rs2488457) have been widely examined. We systematically evaluated...

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Veröffentlicht in:	International journal of rheumatic diseases 2019-05, Vol.22 (5), p.769-780
Hauptverfasser:	Wu, Xuangao, Yang, Hye Jeong, Jung Kim, Min, Zhang, Ting, Qiu, Jing Yi, Park, Sunmin
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Arthritis, Rheumatoid - diagnosis Arthritis, Rheumatoid - enzymology Arthritis, Rheumatoid - ethnology Arthritis, Rheumatoid - genetics Asian people Asians Female Gene Frequency Genetic analysis Genetic diversity Genetic Predisposition to Disease genetic variants Humans inflammation Male Meta-analysis Middle Aged Minority & ethnic groups Phenotype Polymorphism, Single Nucleotide Protein Tyrosine Phosphatase, Non-Receptor Type 22 - genetics Protein-tyrosine-phosphatase PTPN22 Rheumatoid arthritis Risk Assessment Risk Factors
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