Synthesis of benzoxazoles via the copper-catalyzed hydroamination of alkynones with 2-aminophenols

We describe herein the synthetic method to benzoxazole derivatives via the copper-catalyzed hydroamination of alkynones with 2-aminophenols. The method produced a wide variety of functionalized benzoxazole derivatives in good yields. Preliminary mechanistic experiments revealed that the reaction wou...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Organic & biomolecular chemistry 2019-04, Vol.17 (17), p.4225-4229
Hauptverfasser:	Oshimoto, Kohei, Tsuji, Hiroaki, Kawatsura, Motoi
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetophenone Chemical synthesis Copper Derivatives
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!