Investigation of the Endoplasmic Reticulum Localization of UDP-Glucuronosyltransferase 2B7 with Systematic Deletion Mutants

UDP-Glucuronosyltransferase (UGT) plays an important role in the metabolism of endogenous and exogenous compounds. UGT is a type I membrane protein, and has a dilysine motif (KKXX/KXKXX) in its C-terminal cytoplasmic domain. Although a dilysine motif is defined as an endoplasmic reticulum (ER) retri...

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Veröffentlicht in:Molecular pharmacology 2019-05, Vol.95 (5), p.551-562
Hauptverfasser: Miyauchi, Yuu, Kimura, Sora, Kimura, Akane, Kurohara, Ken, Hirota, Yuko, Fujimoto, Keiko, Mackenzie, Peter I., Tanaka, Yoshitaka, Ishii, Yuji
Format: Artikel
Sprache:eng
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