Sodium butyrate suppresses NOD1‐mediated inflammatory molecules expressed in bovine hepatocytes during iE‐DAP and LPS treatment

Nucleotide oligomerization domain protein‐1 (NOD1), a cytosolic pattern recognition receptor for the γ‐D‐glutamyl‐meso‐diaminopimelic acid (iE‐DAP) is associated with the inflammatory diseases. Very little is known how bovine hepatocytes respond to specific ligands of NOD1 and sodium butyrate (SB)....

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Veröffentlicht in:	Journal of cellular physiology 2019-11, Vol.234 (11), p.19602-19620
Hauptverfasser:	Roy, Animesh Chandra, Chang, Guangjun, Ma, Nana, Wang, Yan, Roy, Shipra, Liu, Jing, Aabdin, Zain‐Ul, Shen, Xiangzhen
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute phase proteins bovine hepatocyte CCL20 protein Chemokines Cytokines Defensins Extracellular signal-regulated kinase Hepatocytes iE‐DAP Immune response Immune system inflammation Inflammatory diseases Interferon Kinases Ligands Lipopolysaccharides LPS LRRK2 protein MAP kinase Nitric-oxide synthase Nod1 protein Nucleotides Oligomerization Pattern recognition Pattern recognition receptors Phosphorylation Pretreatment Proteins Sodium Sodium butyrate TAK1 protein Tumor necrosis factor
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