TRAIP regulates Histone H2B monoubiquitination in DNA damage response pathways

Histone H2B monoubiquitination has been shown to play critical roles in diverse cellular processes including DNA damage response. Although recent data indicate that H2B monoubiquitination is strongly connected with tumor progression and regulation, the implications of this modification in lung adeno...

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Veröffentlicht in:	Oncology reports 2019-06, Vol.41 (6), p.3305-3312
Hauptverfasser:	Han, Ye Gi, Yun, Miyong, Choi, Minji, Lee, Seok-Geun, Kim, Hongtae
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma Cancer Cancer therapies Cell cycle Chemotherapy Cytotoxicity Deoxyribonucleic acid Development and progression DNA DNA damage DNA methylation DNA repair Enzymes Genetic aspects Health aspects Immunoglobulins Ionizing radiation Lung cancer Lysine Mutagenesis Necrosis Novels Patients Phosphorylation Physiological aspects Plasmids Proteins Radiation (Physics) Radiation therapy Recruitment Signal transduction Signaling peptides and proteins Tumor necrosis factor Tumor necrosis factor-TNF Tumors Ubiquitin-proteasome system
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