Thyroid Function and Cardiovascular Disease: The Mediating Role of Coagulation Factors

Abstract Context Mechanisms linking high and high-normal thyroid function to increased cardiovascular risk remain unclear. Hypothetically, coagulation can play a role. Objective To investigate (i) the association of thyroid function with coagulation factors and (ii) whether coagulation factors media...

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Veröffentlicht in:	The journal of clinical endocrinology and metabolism 2019-08, Vol.104 (8), p.3203-3212
Hauptverfasser:	Bano, Arjola, Chaker, Layal, de Maat, Moniek P M, Atiq, Ferdows, Kavousi, Maryam, Franco, Oscar H, Mattace-Raso, Francesco U S, Leebeek, Frank W G, Peeters, Robin P
Format:	Artikel
Sprache:	eng
Schlagworte:	ADAMTS13 Protein - blood Aged Aged, 80 and over Analysis Blood Coagulation - physiology Cardiovascular disease Cardiovascular diseases Cardiovascular Diseases - blood Cardiovascular Diseases - etiology Cardiovascular Diseases - physiopathology Coagulation factors Female Fibrin Fibrinogen Fibrinogen - analysis Health risk assessment Humans Male Mediation Middle Aged Pharmaceutical industry Population studies Proportional Hazards Models Prospective Studies Regression analysis Thyroid Thyroid gland Thyroid Gland - physiopathology Thyroid-stimulating hormone Thyroxine Thyroxine - blood Von Willebrand factor von Willebrand Factor - analysis
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