Homeobox D10, a tumor suppressor, inhibits the proliferation and migration of esophageal squamous cell carcinoma

Esophageal squamous cell carcinoma (ESCC) is one of the most common types of esophageal cancer, which is the sixth leading cause of cancer death globally. Homeobox D10 (HOXD10) is a member of the homeobox (HOX) gene family and has been reported to act as a tumor suppressor. However, the potential ro...

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Veröffentlicht in:	Journal of cellular biochemistry 2019-08, Vol.120 (8), p.13717-13725
Hauptverfasser:	Zhang, Jin, Liu, Shiyuan, Zhang, Danjie, Ma, Zhenchuan, Sun, Liangzhang
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Phosphatidylinositol 3-kinase AKT protein Biotechnology Cancer Cell growth Cell migration Cell proliferation Cholecystokinin Ectopic expression epithelial‐mesenchymal transition (EMT) Esophageal cancer esophageal squamous cell carcinoma (ESCC) Esophagus Growth factors Homeobox Homeobox D10 (HOXD10) In vivo methods and tests Insulin invasion Kinases Mesenchyme migration PI3K/AKT/mTOR signaling pathway Polymerase chain reaction Proteins Reverse transcription Signal transduction Signaling Squamous cell carcinoma TOR protein Tumor suppressor genes Tumors
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