Prevalence of antiphospholipid antibodies among patients with chronic thromboembolic pulmonary hypertension

In most cases of acute pulmonary embolism, fbrinolysis of the embolus takes place, restoring blood fow and normalizing hemodynamic parameters. However, in a minority of patients, a residual organized clot remains adherent to the pulmonary vasculature which, over time, results in a progressive increa...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Internal and emergency medicine 2019-06, Vol.14 (4), p.495-496
Hauptverfasser: Cervi, Andrea, Douketis, James Demetrios
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 496
container_issue 4
container_start_page 495
container_title Internal and emergency medicine
container_volume 14
creator Cervi, Andrea
Douketis, James Demetrios
description In most cases of acute pulmonary embolism, fbrinolysis of the embolus takes place, restoring blood fow and normalizing hemodynamic parameters. However, in a minority of patients, a residual organized clot remains adherent to the pulmonary vasculature which, over time, results in a progressive increase in pulmonary vascular resistance. This condition, known as chronic thromboembolic pulmonary hypertension (CTEPH), is a rare complication of pulmonary embolism that is characterized by the presence of persistent and organized thrombi in the proximal pulmonary arteries [1, 2]. Poor thrombus resolution due to inadequate fbrinolysis and/or recurrent thrombosis likely predispose towards the development of CTEPH. However, why only a small subset of patients go on to develop CTEPH following acute pulmonary embolism remains uncertain.
doi_str_mv 10.1007/s11739-019-02078-4
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2202195578</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2201460947</sourcerecordid><originalsourceid>FETCH-LOGICAL-c326t-93d55f68d77fb01c93c60c7ae965721bed598a1057220e2a194d95aa63b16ba33</originalsourceid><addsrcrecordid>eNp9kU1P3DAQhq2KqsDSP9ADisSllxQ7ju34iBD9kJDKoZwtx5nsGhI72AnV_vsO7EIlDhxG47Gf-fC8hHxh9BujVJ1nxhTXJWVoFVVNWX8gR0wrWmou5QGem6opaV2rQ3Kc8x2lQkimPpFDTjVXDedH5P4mwaMdIDgoYl_YMPtpEzPa4CffPV-0sfOQCzvGsC4mO3sIcy7--nlTuE2KwbtiRj-2EdAGDKdlQNimbbHZTpBmCNnHcEI-9nbI8HnvV-T2-9Wfy5_l9e8fvy4vrkvHKznj8J0QvWw6pfqWMqe5k9QpC1oKVbEWOqEbyygGFYXKMl13Wlgrectkazlfka-7ulOKDwvk2Yw-OxgGGyAu2WBaxbQQuIEVOXuD3sUlBZzuiWK1pLpWSFU7yqWYc4LeTMmP-D3DqHmSwuykMCiFeZbC1Jh0ui-9tCN0rykvu0eA74CMT2EN6X_vd8r-A7dJlgY</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2201460947</pqid></control><display><type>article</type><title>Prevalence of antiphospholipid antibodies among patients with chronic thromboembolic pulmonary hypertension</title><source>MEDLINE</source><source>Springer Journals</source><creator>Cervi, Andrea ; Douketis, James Demetrios</creator><creatorcontrib>Cervi, Andrea ; Douketis, James Demetrios</creatorcontrib><description>In most cases of acute pulmonary embolism, fbrinolysis of the embolus takes place, restoring blood fow and normalizing hemodynamic parameters. However, in a minority of patients, a residual organized clot remains adherent to the pulmonary vasculature which, over time, results in a progressive increase in pulmonary vascular resistance. This condition, known as chronic thromboembolic pulmonary hypertension (CTEPH), is a rare complication of pulmonary embolism that is characterized by the presence of persistent and organized thrombi in the proximal pulmonary arteries [1, 2]. Poor thrombus resolution due to inadequate fbrinolysis and/or recurrent thrombosis likely predispose towards the development of CTEPH. However, why only a small subset of patients go on to develop CTEPH following acute pulmonary embolism remains uncertain.</description><identifier>ISSN: 1828-0447</identifier><identifier>EISSN: 1970-9366</identifier><identifier>DOI: 10.1007/s11739-019-02078-4</identifier><identifier>PMID: 30937833</identifier><language>eng</language><publisher>Cham: Springer International Publishing</publisher><subject>Antibodies, Antiphospholipid ; Anticoagulants ; Antiphospholipid antibodies ; Blood clots ; Embolisms ; Emergency medical care ; Epidemiology ; Health risk assessment ; Humans ; Hypertension, Pulmonary ; Im - Commentary ; Immunoglobulins ; Internal Medicine ; Medicine ; Medicine &amp; Public Health ; Prevalence ; Proteins ; Pulmonary arteries ; Pulmonary artery ; Pulmonary hypertension ; Studies ; Systematic review ; Thromboembolism ; Thrombosis</subject><ispartof>Internal and emergency medicine, 2019-06, Vol.14 (4), p.495-496</ispartof><rights>Società Italiana di Medicina Interna (SIMI) 2019</rights><rights>Internal and Emergency Medicine is a copyright of Springer, (2019). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c326t-93d55f68d77fb01c93c60c7ae965721bed598a1057220e2a194d95aa63b16ba33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11739-019-02078-4$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s11739-019-02078-4$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>315,782,786,27931,27932,41495,42564,51326</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30937833$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cervi, Andrea</creatorcontrib><creatorcontrib>Douketis, James Demetrios</creatorcontrib><title>Prevalence of antiphospholipid antibodies among patients with chronic thromboembolic pulmonary hypertension</title><title>Internal and emergency medicine</title><addtitle>Intern Emerg Med</addtitle><addtitle>Intern Emerg Med</addtitle><description>In most cases of acute pulmonary embolism, fbrinolysis of the embolus takes place, restoring blood fow and normalizing hemodynamic parameters. However, in a minority of patients, a residual organized clot remains adherent to the pulmonary vasculature which, over time, results in a progressive increase in pulmonary vascular resistance. This condition, known as chronic thromboembolic pulmonary hypertension (CTEPH), is a rare complication of pulmonary embolism that is characterized by the presence of persistent and organized thrombi in the proximal pulmonary arteries [1, 2]. Poor thrombus resolution due to inadequate fbrinolysis and/or recurrent thrombosis likely predispose towards the development of CTEPH. However, why only a small subset of patients go on to develop CTEPH following acute pulmonary embolism remains uncertain.</description><subject>Antibodies, Antiphospholipid</subject><subject>Anticoagulants</subject><subject>Antiphospholipid antibodies</subject><subject>Blood clots</subject><subject>Embolisms</subject><subject>Emergency medical care</subject><subject>Epidemiology</subject><subject>Health risk assessment</subject><subject>Humans</subject><subject>Hypertension, Pulmonary</subject><subject>Im - Commentary</subject><subject>Immunoglobulins</subject><subject>Internal Medicine</subject><subject>Medicine</subject><subject>Medicine &amp; Public Health</subject><subject>Prevalence</subject><subject>Proteins</subject><subject>Pulmonary arteries</subject><subject>Pulmonary artery</subject><subject>Pulmonary hypertension</subject><subject>Studies</subject><subject>Systematic review</subject><subject>Thromboembolism</subject><subject>Thrombosis</subject><issn>1828-0447</issn><issn>1970-9366</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp9kU1P3DAQhq2KqsDSP9ADisSllxQ7ju34iBD9kJDKoZwtx5nsGhI72AnV_vsO7EIlDhxG47Gf-fC8hHxh9BujVJ1nxhTXJWVoFVVNWX8gR0wrWmou5QGem6opaV2rQ3Kc8x2lQkimPpFDTjVXDedH5P4mwaMdIDgoYl_YMPtpEzPa4CffPV-0sfOQCzvGsC4mO3sIcy7--nlTuE2KwbtiRj-2EdAGDKdlQNimbbHZTpBmCNnHcEI-9nbI8HnvV-T2-9Wfy5_l9e8fvy4vrkvHKznj8J0QvWw6pfqWMqe5k9QpC1oKVbEWOqEbyygGFYXKMl13Wlgrectkazlfka-7ulOKDwvk2Yw-OxgGGyAu2WBaxbQQuIEVOXuD3sUlBZzuiWK1pLpWSFU7yqWYc4LeTMmP-D3DqHmSwuykMCiFeZbC1Jh0ui-9tCN0rykvu0eA74CMT2EN6X_vd8r-A7dJlgY</recordid><startdate>20190601</startdate><enddate>20190601</enddate><creator>Cervi, Andrea</creator><creator>Douketis, James Demetrios</creator><general>Springer International Publishing</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7T5</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20190601</creationdate><title>Prevalence of antiphospholipid antibodies among patients with chronic thromboembolic pulmonary hypertension</title><author>Cervi, Andrea ; Douketis, James Demetrios</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c326t-93d55f68d77fb01c93c60c7ae965721bed598a1057220e2a194d95aa63b16ba33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Antibodies, Antiphospholipid</topic><topic>Anticoagulants</topic><topic>Antiphospholipid antibodies</topic><topic>Blood clots</topic><topic>Embolisms</topic><topic>Emergency medical care</topic><topic>Epidemiology</topic><topic>Health risk assessment</topic><topic>Humans</topic><topic>Hypertension, Pulmonary</topic><topic>Im - Commentary</topic><topic>Immunoglobulins</topic><topic>Internal Medicine</topic><topic>Medicine</topic><topic>Medicine &amp; Public Health</topic><topic>Prevalence</topic><topic>Proteins</topic><topic>Pulmonary arteries</topic><topic>Pulmonary artery</topic><topic>Pulmonary hypertension</topic><topic>Studies</topic><topic>Systematic review</topic><topic>Thromboembolism</topic><topic>Thrombosis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cervi, Andrea</creatorcontrib><creatorcontrib>Douketis, James Demetrios</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Nursing and Allied Health Journals</collection><collection>Immunology Abstracts</collection><collection>Health &amp; Medical Collection (Proquest)</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Family Health Database (Proquest)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Internal and emergency medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cervi, Andrea</au><au>Douketis, James Demetrios</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prevalence of antiphospholipid antibodies among patients with chronic thromboembolic pulmonary hypertension</atitle><jtitle>Internal and emergency medicine</jtitle><stitle>Intern Emerg Med</stitle><addtitle>Intern Emerg Med</addtitle><date>2019-06-01</date><risdate>2019</risdate><volume>14</volume><issue>4</issue><spage>495</spage><epage>496</epage><pages>495-496</pages><issn>1828-0447</issn><eissn>1970-9366</eissn><abstract>In most cases of acute pulmonary embolism, fbrinolysis of the embolus takes place, restoring blood fow and normalizing hemodynamic parameters. However, in a minority of patients, a residual organized clot remains adherent to the pulmonary vasculature which, over time, results in a progressive increase in pulmonary vascular resistance. This condition, known as chronic thromboembolic pulmonary hypertension (CTEPH), is a rare complication of pulmonary embolism that is characterized by the presence of persistent and organized thrombi in the proximal pulmonary arteries [1, 2]. Poor thrombus resolution due to inadequate fbrinolysis and/or recurrent thrombosis likely predispose towards the development of CTEPH. However, why only a small subset of patients go on to develop CTEPH following acute pulmonary embolism remains uncertain.</abstract><cop>Cham</cop><pub>Springer International Publishing</pub><pmid>30937833</pmid><doi>10.1007/s11739-019-02078-4</doi><tpages>2</tpages></addata></record>
fulltext fulltext
identifier ISSN: 1828-0447
ispartof Internal and emergency medicine, 2019-06, Vol.14 (4), p.495-496
issn 1828-0447
1970-9366
language eng
recordid cdi_proquest_miscellaneous_2202195578
source MEDLINE; Springer Journals
subjects Antibodies, Antiphospholipid
Anticoagulants
Antiphospholipid antibodies
Blood clots
Embolisms
Emergency medical care
Epidemiology
Health risk assessment
Humans
Hypertension, Pulmonary
Im - Commentary
Immunoglobulins
Internal Medicine
Medicine
Medicine & Public Health
Prevalence
Proteins
Pulmonary arteries
Pulmonary artery
Pulmonary hypertension
Studies
Systematic review
Thromboembolism
Thrombosis
title Prevalence of antiphospholipid antibodies among patients with chronic thromboembolic pulmonary hypertension
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-06T18%3A41%3A22IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Prevalence%20of%20antiphospholipid%20antibodies%20among%20patients%20with%20chronic%20thromboembolic%20pulmonary%20hypertension&rft.jtitle=Internal%20and%20emergency%20medicine&rft.au=Cervi,%20Andrea&rft.date=2019-06-01&rft.volume=14&rft.issue=4&rft.spage=495&rft.epage=496&rft.pages=495-496&rft.issn=1828-0447&rft.eissn=1970-9366&rft_id=info:doi/10.1007/s11739-019-02078-4&rft_dat=%3Cproquest_cross%3E2201460947%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2201460947&rft_id=info:pmid/30937833&rfr_iscdi=true