Gonadoblastoma Y locus genes expressed in germ cells of individuals with dysgenetic gonads and a Y chromosome in their karyotypes include DDX3Y and TSPY

Abstract STUDY QUESTION Which Y genes mapped to the 'Gonadoblastoma Y (GBY)' locus on human Y chromosome are expressed in germ cells of individuals with some Differences of Sexual Development (DSD) and a Y chromosome in their karyotype (DSD-XY groups)? SUMMARY ANSWER The GBY candidate gene...

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Veröffentlicht in:	Human reproduction (Oxford) 2019-04, Vol.34 (4), p.770-779
Hauptverfasser:	Vogt, P H, Besikoglu, B, Bettendorf, M, Frank-Herrmann, P, Zimmer, J, Bender, U, Knauer-Fischer, S, Choukair, D, Sinn, P, Lau, Y-F C, Heidemann, P H, Strowitzki, T
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Biopsy Cell Cycle Proteins - genetics Cell Cycle Proteins - metabolism Child Child, Preschool Chromosomes, Human, Y - metabolism DEAD-box RNA Helicases - genetics DEAD-box RNA Helicases - metabolism Female Gene Expression Regulation, Neoplastic Genetic Loci Germ Cells - metabolism Gonadoblastoma - blood Gonadoblastoma - genetics Gonadoblastoma - pathology Gonads - pathology Humans Infant Karyotype Male Minor Histocompatibility Antigens - genetics Minor Histocompatibility Antigens - metabolism Ovarian Neoplasms - blood Ovarian Neoplasms - genetics Ovarian Neoplasms - pathology Testicular Neoplasms - blood Testicular Neoplasms - genetics Testicular Neoplasms - pathology Young Adult
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