Human Placenta Hydrolysate Promotes Liver Regeneration via Activation of the Cytokine/Growth Factor-Mediated Pathway and Anti-oxidative Effect

Liver regeneration is a very complex process and is regulated by several cytokines and growth factors. It is also known that liver transplantation and the regeneration process cause massive oxidative stress, which interferes with liver regeneration. The placenta is known to contain various physiolog...

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Veröffentlicht in:	Biological & pharmaceutical bulletin 2019/04/01, Vol.42(4), pp.607-616
Hauptverfasser:	Lee, Tae Hee, Park, Dong Sun, Jang, Ja Young, Lee, Isaac, Kim, Jong Man, Choi, Gyu Seong, Oh, Chang Taek, Kim, Jeom Yong, Han, Hae Jung, Han, Beom Seok, Joh, Jae Won
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Animals anti-oxidative stress Antioxidants - physiology Bile Cell Line Cell proliferation cytokine Cytokines Female Glutathione peroxidase Growth factors Hepatectomy Hepatocyte growth factor Humans Intercellular Signaling Peptides and Proteins - physiology Interleukin 6 Kupffer cells Liver Liver Regeneration Liver transplantation Male Oxidative Stress partial hepatectomy Placenta Pregnancy Proliferating cell nuclear antigen Rats, Sprague-Dawley Signal Transduction Superoxide dismutase Thiobarbituric acid Transplantation Tumor necrosis factor-TNF Tumor necrosis factor-α
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