A Comparative Study of Longitudinal Toxicities of Cytotoxic Drugs, Molecularly Targeted Agents, Immunomodulatory Drugs, and Cancer Vaccines

Little is known about the toxicity of various therapeutics for cancer over time because randomized controlled clinical trials that compare several treatments are limited. In this study, we focused on the toxicities most frequently discussed, which are investigations (lab abnormalities), gastrointest...

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Veröffentlicht in:	Clinical pharmacology and therapeutics 2019-10, Vol.106 (4), p.803-809
Hauptverfasser:	Hirakawa, Akihiro, Sudo, Kazuki, Yonemori, Kan, Sadachi, Ryo, Kinoshita, Fumie, Kobayashi, Yumiko, Okuma, Hitomi S., Kawachi, Asuka, Tamura, Kenji, Fujiwara, Yasuhiro, Rubinstein, Larry, Takebe, Naoko
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - adverse effects Antineoplastic Agents - classification Cancer Vaccines - adverse effects Clinical Trials as Topic Cytotoxins - adverse effects Drug-Related Side Effects and Adverse Reactions - classification Drug-Related Side Effects and Adverse Reactions - epidemiology Drug-Related Side Effects and Adverse Reactions - etiology Female Humans Immunologic Factors - adverse effects Long Term Adverse Effects - chemically induced Long Term Adverse Effects - classification Long Term Adverse Effects - epidemiology Male Middle Aged Molecular Targeted Therapy - adverse effects Neoplasms - drug therapy Prevalence Severity of Illness Index
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