Psoriasiform and acneiform lesions in a patient with bipolar disease
Clinical examination revealed well-defined erythematous scaly papules and plaques with white semiadherent scales with mild-to moderate induration over the scalp, chest, back and upper extremities (figures 1 and 2). [...]the incidence of psoriasis secondary to lithium treatment has been reported to b...
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| Veröffentlicht in: | Postgraduate medical journal 2019-07, Vol.95 (1125), p.391-391 |
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| creator | Guliani, Ankur Yadav, Tek Chand |
| description | Clinical examination revealed well-defined erythematous scaly papules and plaques with white semiadherent scales with mild-to moderate induration over the scalp, chest, back and upper extremities (figures 1 and 2). [...]the incidence of psoriasis secondary to lithium treatment has been reported to be from 1.8% to 6%.1 The mechanism by which lithium induces psoriasis is not clearly understood, however lithium has a role in modulating adenyl cyclase and inositol monophosphatase-mediated pathways.2 The decrease in cyclic adenosine monophosphate and inositol as a result of lithium treatment causes low intracellular levels of calcium, leading to lack of differentiation and increased proliferation of keratinocytes, enhanced chemotaxis and phagocytic activity of polymorphonuclear leucocytes.3 Lithium is associated with a variety of cutaneous side effects including psoriasis. Dermatologists, psychiatrists and family physicians should be aware of this association. [...]early detection can help in avoiding further deterioration of symptoms of bipolar disease secondary to disfguring skin appearance. |
| doi_str_mv | 10.1136/postgradmedj-2018-136329 |
| format | Article |
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[...]the incidence of psoriasis secondary to lithium treatment has been reported to be from 1.8% to 6%.1 The mechanism by which lithium induces psoriasis is not clearly understood, however lithium has a role in modulating adenyl cyclase and inositol monophosphatase-mediated pathways.2 The decrease in cyclic adenosine monophosphate and inositol as a result of lithium treatment causes low intracellular levels of calcium, leading to lack of differentiation and increased proliferation of keratinocytes, enhanced chemotaxis and phagocytic activity of polymorphonuclear leucocytes.3 Lithium is associated with a variety of cutaneous side effects including psoriasis. Dermatologists, psychiatrists and family physicians should be aware of this association. [...]early detection can help in avoiding further deterioration of symptoms of bipolar disease secondary to disfguring skin appearance.</description><identifier>ISSN: 0032-5473</identifier><identifier>EISSN: 1469-0756</identifier><identifier>DOI: 10.1136/postgradmedj-2018-136329</identifier><identifier>PMID: 30926721</identifier><language>eng</language><publisher>England: Oxford University Press</publisher><subject>Acneiform Eruptions - chemically induced ; Acneiform Eruptions - physiopathology ; Adult ; Bipolar disorder ; Bipolar Disorder - diagnosis ; Bipolar Disorder - drug therapy ; Drug Eruptions - etiology ; Drug Eruptions - physiopathology ; Follow-Up Studies ; Humans ; Lithium ; Lithium - adverse effects ; Lithium - therapeutic use ; Male ; Psoriasis ; Psoriasis - chemically induced ; Psoriasis - physiopathology ; Risk Assessment ; Skin</subject><ispartof>Postgraduate medical journal, 2019-07, Vol.95 (1125), p.391-391</ispartof><rights>Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ.</rights><rights>2019 Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. 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[...]the incidence of psoriasis secondary to lithium treatment has been reported to be from 1.8% to 6%.1 The mechanism by which lithium induces psoriasis is not clearly understood, however lithium has a role in modulating adenyl cyclase and inositol monophosphatase-mediated pathways.2 The decrease in cyclic adenosine monophosphate and inositol as a result of lithium treatment causes low intracellular levels of calcium, leading to lack of differentiation and increased proliferation of keratinocytes, enhanced chemotaxis and phagocytic activity of polymorphonuclear leucocytes.3 Lithium is associated with a variety of cutaneous side effects including psoriasis. Dermatologists, psychiatrists and family physicians should be aware of this association. [...]early detection can help in avoiding further deterioration of symptoms of bipolar disease secondary to disfguring skin appearance.</description><subject>Acneiform Eruptions - chemically induced</subject><subject>Acneiform Eruptions - physiopathology</subject><subject>Adult</subject><subject>Bipolar disorder</subject><subject>Bipolar Disorder - diagnosis</subject><subject>Bipolar Disorder - drug therapy</subject><subject>Drug Eruptions - etiology</subject><subject>Drug Eruptions - physiopathology</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Lithium</subject><subject>Lithium - adverse effects</subject><subject>Lithium - therapeutic use</subject><subject>Male</subject><subject>Psoriasis</subject><subject>Psoriasis - chemically induced</subject><subject>Psoriasis - physiopathology</subject><subject>Risk Assessment</subject><subject>Skin</subject><issn>0032-5473</issn><issn>1469-0756</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqNkE1LxDAQhoMo7rr6FyTgxUs1maRJe5T1Exb0oOeQtqmmtE1NWsR_b5auIp48DZk8M_PyIIQpuaCUicvBhfHV66ozVZMAoVkSuwzyPbSkXOQJkanYR0tCGCQpl2yBjkJoCKFMcnqIFozkICTQJbp-Cs5bHWztfId1X2Fd9mZ-tSZY1wdse6zxoEdr-hF_2PENF3Zwrfa4ssHoYI7RQa3bYE52dYVebm-e1_fJ5vHuYX21SQqWyTFhrJAZcKgII6asgHCdCVrKXArBRV3UAKKuYl6dFVyaGJ7rHIwkteQgS2ArdD7vHbx7n0wYVWdDadpW98ZNQQEQEi9QKiJ69gdt3OT7mC5SKYNUZjKPVDZTpXcheFOrwdtO-09FidqaVr9Nq61pNZuOo6e7A1MRP38Gv9VGgM1A0TX_X_sFLiGMvQ</recordid><startdate>20190701</startdate><enddate>20190701</enddate><creator>Guliani, Ankur</creator><creator>Yadav, Tek Chand</creator><general>Oxford University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-4170-9983</orcidid></search><sort><creationdate>20190701</creationdate><title>Psoriasiform and acneiform lesions in a patient with bipolar disease</title><author>Guliani, Ankur ; Yadav, Tek Chand</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b387t-33b78242d030ecd204a861c7976646fbf226fd547a8b47e0324a92e70f7427c23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Acneiform Eruptions - chemically induced</topic><topic>Acneiform Eruptions - physiopathology</topic><topic>Adult</topic><topic>Bipolar disorder</topic><topic>Bipolar Disorder - diagnosis</topic><topic>Bipolar Disorder - drug therapy</topic><topic>Drug Eruptions - etiology</topic><topic>Drug Eruptions - physiopathology</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Lithium</topic><topic>Lithium - adverse effects</topic><topic>Lithium - therapeutic use</topic><topic>Male</topic><topic>Psoriasis</topic><topic>Psoriasis - chemically induced</topic><topic>Psoriasis - physiopathology</topic><topic>Risk Assessment</topic><topic>Skin</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Guliani, Ankur</creatorcontrib><creatorcontrib>Yadav, Tek Chand</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Postgraduate medical journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Guliani, Ankur</au><au>Yadav, Tek Chand</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Psoriasiform and acneiform lesions in a patient with bipolar disease</atitle><jtitle>Postgraduate medical journal</jtitle><addtitle>Postgrad Med J</addtitle><date>2019-07-01</date><risdate>2019</risdate><volume>95</volume><issue>1125</issue><spage>391</spage><epage>391</epage><pages>391-391</pages><issn>0032-5473</issn><eissn>1469-0756</eissn><abstract>Clinical examination revealed well-defined erythematous scaly papules and plaques with white semiadherent scales with mild-to moderate induration over the scalp, chest, back and upper extremities (figures 1 and 2). [...]the incidence of psoriasis secondary to lithium treatment has been reported to be from 1.8% to 6%.1 The mechanism by which lithium induces psoriasis is not clearly understood, however lithium has a role in modulating adenyl cyclase and inositol monophosphatase-mediated pathways.2 The decrease in cyclic adenosine monophosphate and inositol as a result of lithium treatment causes low intracellular levels of calcium, leading to lack of differentiation and increased proliferation of keratinocytes, enhanced chemotaxis and phagocytic activity of polymorphonuclear leucocytes.3 Lithium is associated with a variety of cutaneous side effects including psoriasis. Dermatologists, psychiatrists and family physicians should be aware of this association. [...]early detection can help in avoiding further deterioration of symptoms of bipolar disease secondary to disfguring skin appearance.</abstract><cop>England</cop><pub>Oxford University Press</pub><pmid>30926721</pmid><doi>10.1136/postgradmedj-2018-136329</doi><tpages>1</tpages><orcidid>https://orcid.org/0000-0003-4170-9983</orcidid></addata></record> |
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| subjects | Acneiform Eruptions - chemically induced Acneiform Eruptions - physiopathology Adult Bipolar disorder Bipolar Disorder - diagnosis Bipolar Disorder - drug therapy Drug Eruptions - etiology Drug Eruptions - physiopathology Follow-Up Studies Humans Lithium Lithium - adverse effects Lithium - therapeutic use Male Psoriasis Psoriasis - chemically induced Psoriasis - physiopathology Risk Assessment Skin |
| title | Psoriasiform and acneiform lesions in a patient with bipolar disease |
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