Clinicopathologic features and prognosis of patients with IgA nephropathy superimposed on transplant glomerulopathy
To observe the clinicopathologic features and prognostic of patients with IgA nephropathy (IgAN) superimposed on transplant glomerulopathy (TG+ IgAN). Electronic medical records of Jinling Hospital were searched for TG+ IgAN patients that was diagnosed during January 2004 to December 2016. Clinicopa...
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Veröffentlicht in: | Zhong hua yi xue za zhi 2019-03, Vol.99 (12), p.889-894 |
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creator | Li, X Chen, J S Cheng, D R Ji, S M Xie, K N Ni, X F Wen, J Q Tang, Z |
description | To observe the clinicopathologic features and prognostic of patients with IgA nephropathy (IgAN) superimposed on transplant glomerulopathy (TG+ IgAN).
Electronic medical records of Jinling Hospital were searched for TG+ IgAN patients that was diagnosed during January 2004 to December 2016. Clinicopathologic features and prognoses information were retrieved and analyzed. The primary outcome was initiation of replacement therapy or an eGFR declined to |
doi_str_mv | 10.3760/cma.j.issn.0376-2491.2019.12.003 |
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Electronic medical records of Jinling Hospital were searched for TG+ IgAN patients that was diagnosed during January 2004 to December 2016. Clinicopathologic features and prognoses information were retrieved and analyzed. The primary outcome was initiation of replacement therapy or an eGFR declined to<15 ml·min(-1)·(1.73m(2))(-1).
A total of 49 patients with pathologically confirmed TG+ IgAN were enrolled in this study. The median time from renal transplantation to allograft biopsy was 85 months. There were 131 patients with TG in the control group. There was no statistical difference in the age, gender, and immunosuppressive regimen during renal biopsy in the two groups. In TG+ IgAN patients, the median serum creatinine level was 175 μmol/L, the median urinary protein was 1.45 g/24 h, and 16.3% of the patients had nephrotic range proteinuria, the incidence of</description><identifier>ISSN: 0376-2491</identifier><identifier>DOI: 10.3760/cma.j.issn.0376-2491.2019.12.003</identifier><identifier>PMID: 30917436</identifier><language>chi</language><publisher>China</publisher><subject>Biopsy ; Glomerulonephritis, IGA ; Humans ; Kidney Glomerulus ; Kidney Transplantation ; Prognosis ; Proteinuria</subject><ispartof>Zhong hua yi xue za zhi, 2019-03, Vol.99 (12), p.889-894</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30917436$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Li, X</creatorcontrib><creatorcontrib>Chen, J S</creatorcontrib><creatorcontrib>Cheng, D R</creatorcontrib><creatorcontrib>Ji, S M</creatorcontrib><creatorcontrib>Xie, K N</creatorcontrib><creatorcontrib>Ni, X F</creatorcontrib><creatorcontrib>Wen, J Q</creatorcontrib><creatorcontrib>Tang, Z</creatorcontrib><title>Clinicopathologic features and prognosis of patients with IgA nephropathy superimposed on transplant glomerulopathy</title><title>Zhong hua yi xue za zhi</title><addtitle>Zhonghua Yi Xue Za Zhi</addtitle><description>To observe the clinicopathologic features and prognostic of patients with IgA nephropathy (IgAN) superimposed on transplant glomerulopathy (TG+ IgAN).
Electronic medical records of Jinling Hospital were searched for TG+ IgAN patients that was diagnosed during January 2004 to December 2016. Clinicopathologic features and prognoses information were retrieved and analyzed. The primary outcome was initiation of replacement therapy or an eGFR declined to<15 ml·min(-1)·(1.73m(2))(-1).
A total of 49 patients with pathologically confirmed TG+ IgAN were enrolled in this study. The median time from renal transplantation to allograft biopsy was 85 months. There were 131 patients with TG in the control group. There was no statistical difference in the age, gender, and immunosuppressive regimen during renal biopsy in the two groups. In TG+ IgAN patients, the median serum creatinine level was 175 μmol/L, the median urinary protein was 1.45 g/24 h, and 16.3% of the patients had nephrotic range proteinuria, the incidence of</description><subject>Biopsy</subject><subject>Glomerulonephritis, IGA</subject><subject>Humans</subject><subject>Kidney Glomerulus</subject><subject>Kidney Transplantation</subject><subject>Prognosis</subject><subject>Proteinuria</subject><issn>0376-2491</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kEtrwzAQhHVoaUKav1B0zCWuXpatYwh9BAK95G7W1tpRsSXXsin59zVN2tPA8O0ws4RsOEtkptlz1UHymbgYfcJmYyuU4Ylg3CRcJIzJO7L89xdkHaMrmcqkEUzwB7KQzPBMSb0kcd8676rQw3gObWhcRWuEcRowUvCW9kNofIgu0lDTGXLox0i_3Ximh2ZHPfbn4ff4QuPU4-C6PkS0NHg6DuBj34IfadOGDoepvZKP5L6GNuL6pityen057d-3x4-3w3533Pap1lsOGWYVZEwiz2UNFjgIUKkCiyZPtcoFsxrq0qKQqrZGK5HaCnKppM3yUq7I5ho7b_iaMI5F52KF7dwIwxQLwY2Zk1mqZ_Tphk5lh7bo5x0wXIq_P8kfowNxbg</recordid><startdate>20190326</startdate><enddate>20190326</enddate><creator>Li, X</creator><creator>Chen, J S</creator><creator>Cheng, D R</creator><creator>Ji, S M</creator><creator>Xie, K N</creator><creator>Ni, X F</creator><creator>Wen, J Q</creator><creator>Tang, Z</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20190326</creationdate><title>Clinicopathologic features and prognosis of patients with IgA nephropathy superimposed on transplant glomerulopathy</title><author>Li, X ; Chen, J S ; Cheng, D R ; Ji, S M ; Xie, K N ; Ni, X F ; Wen, J Q ; Tang, Z</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p566-1a7e7ca703e183fada1a2a454ade98564820d6afbde234fd96425dca8343d78b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>chi</language><creationdate>2019</creationdate><topic>Biopsy</topic><topic>Glomerulonephritis, IGA</topic><topic>Humans</topic><topic>Kidney Glomerulus</topic><topic>Kidney Transplantation</topic><topic>Prognosis</topic><topic>Proteinuria</topic><toplevel>online_resources</toplevel><creatorcontrib>Li, X</creatorcontrib><creatorcontrib>Chen, J S</creatorcontrib><creatorcontrib>Cheng, D R</creatorcontrib><creatorcontrib>Ji, S M</creatorcontrib><creatorcontrib>Xie, K N</creatorcontrib><creatorcontrib>Ni, X F</creatorcontrib><creatorcontrib>Wen, J Q</creatorcontrib><creatorcontrib>Tang, Z</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Zhong hua yi xue za zhi</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Li, X</au><au>Chen, J S</au><au>Cheng, D R</au><au>Ji, S M</au><au>Xie, K N</au><au>Ni, X F</au><au>Wen, J Q</au><au>Tang, Z</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinicopathologic features and prognosis of patients with IgA nephropathy superimposed on transplant glomerulopathy</atitle><jtitle>Zhong hua yi xue za zhi</jtitle><addtitle>Zhonghua Yi Xue Za Zhi</addtitle><date>2019-03-26</date><risdate>2019</risdate><volume>99</volume><issue>12</issue><spage>889</spage><epage>894</epage><pages>889-894</pages><issn>0376-2491</issn><abstract>To observe the clinicopathologic features and prognostic of patients with IgA nephropathy (IgAN) superimposed on transplant glomerulopathy (TG+ IgAN).
Electronic medical records of Jinling Hospital were searched for TG+ IgAN patients that was diagnosed during January 2004 to December 2016. Clinicopathologic features and prognoses information were retrieved and analyzed. The primary outcome was initiation of replacement therapy or an eGFR declined to<15 ml·min(-1)·(1.73m(2))(-1).
A total of 49 patients with pathologically confirmed TG+ IgAN were enrolled in this study. The median time from renal transplantation to allograft biopsy was 85 months. There were 131 patients with TG in the control group. There was no statistical difference in the age, gender, and immunosuppressive regimen during renal biopsy in the two groups. In TG+ IgAN patients, the median serum creatinine level was 175 μmol/L, the median urinary protein was 1.45 g/24 h, and 16.3% of the patients had nephrotic range proteinuria, the incidence of</abstract><cop>China</cop><pmid>30917436</pmid><doi>10.3760/cma.j.issn.0376-2491.2019.12.003</doi><tpages>6</tpages></addata></record> |
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source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
subjects | Biopsy Glomerulonephritis, IGA Humans Kidney Glomerulus Kidney Transplantation Prognosis Proteinuria |
title | Clinicopathologic features and prognosis of patients with IgA nephropathy superimposed on transplant glomerulopathy |
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