Propagation of Protein Aggregation in Neurodegenerative Diseases

Most common neurodegenerative diseases feature deposition of protein amyloids and degeneration of brain networks. Amyloids are ordered protein assemblies that can act as templates for their own replication through monomer addition. Evidence suggests that this characteristic may underlie the progress...

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Veröffentlicht in:	Annual review of biochemistry 2019-06, Vol.88 (1), p.785-810
Hauptverfasser:	Vaquer-Alicea, Jaime, Diamond, Marc I
Format:	Artikel
Sprache:	eng
Schlagworte:	aggregation amyloid prion propagation strain tau
Online-Zugang:	Volltext
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