A comprehensive review of topoisomerase inhibitors as anticancer agents in the past decade

The topoisomerase enzymes play an important role in DNA metabolism, and searching for enzyme inhibitors is an important target in the search for new anticancer drugs. Discovery of new anticancer chemotherapeutical capable of inhibiting topoisomerase enzymes is highlighted in anticancer research. The...

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Veröffentlicht in:	European journal of medicinal chemistry 2019-06, Vol.171, p.129-168
Hauptverfasser:	Liang, Xiaoxia, Wu, Qiang, Luan, Shangxian, Yin, Zhongqiong, He, Changliang, Yin, Lizi, Zou, Yuanfeng, Yuan, Zhixiang, Li, Lixia, Song, Xu, He, Min, Lv, Cheng, Zhang, Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticancer compounds Antiproliferative activity Topoisomerase inhibitor
Online-Zugang:	Volltext
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