Collagen facilitates the colorectal cancer stemness and metastasis through an integrin/PI3K/AKT/Snail signaling pathway

Dynamic remodeling of the extracellular matrix (ECM) around tumor cells is crucial for the tumor progressions. However, the mechanism is not well defined. Here, we aimed to reveal the underlying mechanism of ECM induced metastasis and provide innovative strategy to suppress the distant metastasis in...

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Veröffentlicht in:	Biomedicine & pharmacotherapy 2019-06, Vol.114, p.108708-108708, Article 108708
Hauptverfasser:	Wu, Xiangbin, Cai, Jianhui, Zuo, Zhigui, Li, Jinlei
Format:	Artikel
Sprache:	eng
Schlagworte:	Colorectal cancer EMT PI3K/AKT pathway Snail Type I collagen
Online-Zugang:	Volltext
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