Extracellular Vesicles Long RNA Sequencing Reveals Abundant mRNA, circRNA, and lncRNA in Human Blood as Potential Biomarkers for Cancer Diagnosis

Extracellular vesicles (EVs) contain a rich cargo of different RNA species with specialized functions and clinical applications. However, the landscape and characteristics of extracellular vesicle long RNA (exLR) in human blood remain largely unknown. We presented an optimized strategy for exLR sequ...

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Veröffentlicht in:	Clinical chemistry (Baltimore, Md.) Md.), 2019-06, Vol.65 (6), p.798-808
Hauptverfasser:	Li, Yuchen, Zhao, Jingjing, Yu, Shulin, Wang, Zhen, He, Xigan, Su, Yonghui, Guo, Tianan, Sheng, Haoyue, Chen, Jie, Zheng, Qiupeng, Li, Yan, Guo, Weijie, Cai, Xiaohong, Shi, Guohai, Wu, Jiong, Wang, Lu, Wang, Peng, He, Xianghuo, Huang, Shenglin
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers, Tumor - blood Extracellular Vesicles - metabolism Female Humans Male Neoplasms - blood Neoplasms - diagnosis RNA, Circular - blood RNA, Circular - genetics RNA, Long Noncoding - blood RNA, Long Noncoding - genetics RNA, Messenger - blood RNA, Messenger - genetics Sequence Analysis, RNA
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