Multi‐Omics Profiling for NF1 Target Discovery in Neurofibromin (NF1) Deficient Cells

Loss of NF1 is an oncogenic driver. In efforts to define pathways responsible for the development of neurofibromas and other cancers, transcriptomic and proteomic changes are evaluated in a non‐malignant NF1 null cell line. NF1 null HEK293 cells were created using CRISPR/Cas9 technology and they are...

Ausführliche Beschreibung