Alkaloids from nux vomica suppresses colon cancer cell growth through Wnt/β‐catenin signaling pathway

Brucine and Strychnine are alkaloids isolated from the seeds of Strychnos nux vomica L., which have long been used as a traditional medicine for the treatment of tumor. However, the effect of Brucine and Strychnine on colorectal cancer (CRC) and the underlying molecular mechanism remain unclear. In...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Phytotherapy research 2019-05, Vol.33 (5), p.1570-1578
Hauptverfasser:	Ren, Hua, Zhao, Jianping, Fan, Dongsheng, Wang, Ze, Zhao, Tingjie, Li, Yuejin, Zhao, Yirui, Adelson, David, Hao, Huiqin
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenomatous polyposis coli Alkaloids Alkaloids - chemistry Animals Anticancer properties Apoptosis Cancer Catenin Colon Colon cancer Colonic Neoplasms - drug therapy Colonic Neoplasms - pathology Colorectal cancer Colorectal carcinoma Dkk1 protein Exploitation Flow cytometry Humans Mice Mice, Nude Myc protein nux‐vomica Seeds Signal transduction Strychnine Strychnine - analogs & derivatives Strychnine - chemistry Strychnos nux-vomica - chemistry Tumors Wnt protein Wnt Signaling Pathway - drug effects Wnt/β‐catenin signaling pathway Xenografts
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!