Metal-Free C‑2‑H Alkylation of Quinazolin-4-ones with Alkanes via Cross-Dehydrogenative Coupling

A practically useful approach for the cross-dehydrogenative coupling of quinazolin-4-one with simple nonactivated alkanes is reported. The products were smoothly formed under mild reaction conditions, within short reaction time at ambient temperature. The formation of new Csp3-Csp2 bonds occurred at...

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Veröffentlicht in:	Organic letters 2019-04, Vol.21 (7), p.2365-2368
Hauptverfasser:	Mao, Shuai, Luo, Kaixiu, Wang, Lu, Zhao, Hong-Yi, Shergalis, Andrea, Xin, Minhang, Neamati, Nouri, Jin, Yi, Zhang, San-Qi
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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