Functional characterization of PLP fold type IV transaminase with a mixed type of activity from Haliangium ochraceum

Pyridoxal-5′-phosphate (PLP)-dependent transaminases are industrially important enzymes catalyzing the stereoselective amination of ketones and keto acids. Transaminases of PLP fold type IV are characterized by (R)- or (S)-stereoselective transfer of amino groups, depending on the substrate profile...

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Veröffentlicht in:Biochimica et biophysica acta. Proteins and proteomics 2019-06, Vol.1867 (6), p.575-585
Hauptverfasser: Zeifman, Yulia S., Boyko, Konstantin M., Nikolaeva, Alena Yu, Timofeev, Vladimir I., Rakitina, Tatiana V., Popov, Vladimir O., Bezsudnova, Ekaterina Yu
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Sprache:eng
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