Development of a Novel Canine Model of Ischemic Stroke: Skull Base Approach with Transient Middle Cerebral Artery Occlusion

Although canine stroke models have several intrinsic advantages, establishing consistent and reproducible territorial stroke in these models has been challenging because of the abundance of collateral circulation. We have described a skull-base surgical approach that yields reproducible stroke volum...

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Veröffentlicht in:	World neurosurgery 2019-07, Vol.127, p.e251-e260
Hauptverfasser:	Vasquez, Ciro A., Moen, Sean L., Juliano, Mario J., Jagadeesan, Bharathi D., Pluhar, G. Elizabeth, Chen, Clark C., Grande, Andrew W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal stroke Animals Behavior, Animal Brain - pathology Canine Canine stroke Cerebral Angiography Cerebral Arteries - pathology Collateral Circulation Constriction Craniotomy Disease Models, Animal Dogs Electrocoagulation Experimental stroke Infarction, Middle Cerebral Artery - diagnostic imaging Infarction, Middle Cerebral Artery - etiology Infarction, Middle Cerebral Artery - pathology Magnetic Resonance Imaging - methods Male Middle cerebral artery Reproducibility of Results Skull Base - surgery Stroke model
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