Multimodality characteristics of multifocal choroid plexus carcinoma with bilateral calvarial defects in a dog
An 8‐year‐old male intact miniature poodle presented for blindness, obtundation, tetraparesis, and vestibular signs. Magnetic resonance imaging, radiography, and ultrasound revealed a left piriform lobe lesion, right cerebellar and left brainstem lesions, and hydrocephalus and bilateral calvarial de...
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Veröffentlicht in: | Veterinary radiology & ultrasound 2021-05, Vol.62 (3), p.E20-E25 |
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creator | Hughes, Jonathan R. Taylor‐Brown, Frances E. Greville‐Heygate, Oliver Constantino‐Casas, Fernando Williams, David L. Genain, Marie‐Aude |
description | An 8‐year‐old male intact miniature poodle presented for blindness, obtundation, tetraparesis, and vestibular signs. Magnetic resonance imaging, radiography, and ultrasound revealed a left piriform lobe lesion, right cerebellar and left brainstem lesions, and hydrocephalus and bilateral calvarial defects. Histopathology confirmed a choroid plexus carcinoma with meningeal and intraventricular metastases. The calvarial defect did not show evidence of necrosis, osteoclastic resorption, inflammation or neoplastic infiltration, reflecting a quiescent calvarial atrophy or dysplasia. These novel findings supported inclusion of bone atrophy secondary to chronic increased intracranial pressure as a differential diagnosis for large calvarial defects in dogs with choroid plexus carcinoma. |
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Magnetic resonance imaging, radiography, and ultrasound revealed a left piriform lobe lesion, right cerebellar and left brainstem lesions, and hydrocephalus and bilateral calvarial defects. Histopathology confirmed a choroid plexus carcinoma with meningeal and intraventricular metastases. The calvarial defect did not show evidence of necrosis, osteoclastic resorption, inflammation or neoplastic infiltration, reflecting a quiescent calvarial atrophy or dysplasia. These novel findings supported inclusion of bone atrophy secondary to chronic increased intracranial pressure as a differential diagnosis for large calvarial defects in dogs with choroid plexus carcinoma.</description><identifier>ISSN: 1058-8183</identifier><identifier>EISSN: 1740-8261</identifier><identifier>DOI: 10.1111/vru.12732</identifier><identifier>PMID: 30892784</identifier><language>eng</language><publisher>England</publisher><subject>brain neoplasia ; calvarium ; skull defect</subject><ispartof>Veterinary radiology & ultrasound, 2021-05, Vol.62 (3), p.E20-E25</ispartof><rights>2019 American College of Veterinary Radiology</rights><rights>2019 American College of Veterinary Radiology.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3602-d68a3587bfb98e4e54880f49bbcc2ddc17af1f55e63600adb54db35c315418903</citedby><cites>FETCH-LOGICAL-c3602-d68a3587bfb98e4e54880f49bbcc2ddc17af1f55e63600adb54db35c315418903</cites><orcidid>0000-0002-3320-6043 ; 0000-0002-6895-4527</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fvru.12732$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fvru.12732$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30892784$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hughes, Jonathan R.</creatorcontrib><creatorcontrib>Taylor‐Brown, Frances E.</creatorcontrib><creatorcontrib>Greville‐Heygate, Oliver</creatorcontrib><creatorcontrib>Constantino‐Casas, Fernando</creatorcontrib><creatorcontrib>Williams, David L.</creatorcontrib><creatorcontrib>Genain, Marie‐Aude</creatorcontrib><title>Multimodality characteristics of multifocal choroid plexus carcinoma with bilateral calvarial defects in a dog</title><title>Veterinary radiology & ultrasound</title><addtitle>Vet Radiol Ultrasound</addtitle><description>An 8‐year‐old male intact miniature poodle presented for blindness, obtundation, tetraparesis, and vestibular signs. Magnetic resonance imaging, radiography, and ultrasound revealed a left piriform lobe lesion, right cerebellar and left brainstem lesions, and hydrocephalus and bilateral calvarial defects. Histopathology confirmed a choroid plexus carcinoma with meningeal and intraventricular metastases. The calvarial defect did not show evidence of necrosis, osteoclastic resorption, inflammation or neoplastic infiltration, reflecting a quiescent calvarial atrophy or dysplasia. These novel findings supported inclusion of bone atrophy secondary to chronic increased intracranial pressure as a differential diagnosis for large calvarial defects in dogs with choroid plexus carcinoma.</description><subject>brain neoplasia</subject><subject>calvarium</subject><subject>skull defect</subject><issn>1058-8183</issn><issn>1740-8261</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNp10LtOwzAUBmALgWi5DLwA8ghDWl_ixhlRxU0qQkKUNXJ8oUZOXeykpW-PSwobZ_GR_J1_-AG4wGiE04zXoRthUlByAIa4yFHGyQQfph0xnnHM6QCcxPiBEGEFKY7BgCJekoLnQ7B86lxrG6-Es-0WyoUIQrY62NhaGaE3sNkB46Vw6dcHbxVcOf3VRShFkHbpGwE3tl3A2jqRLndOuLUINm1KGy3bCO0SCqj8-xk4MsJFfb5_T8H87vZ1-pDNnu8fpzezTNIJIpmacEEZL2pTl1znmuWcI5OXdS0lUUriQhhsGNOTxJFQNctVTZmkmOWYl4iegqs-dxX8Z6djWzU2Su2cWGrfxYrgMmcJcprodU9l8DEGbapVsI0I2wqjaldvleqtfupN9nIf29WNVn_yt88Exj3YWKe3_ydVby_zPvIb4NaGow</recordid><startdate>202105</startdate><enddate>202105</enddate><creator>Hughes, Jonathan R.</creator><creator>Taylor‐Brown, Frances E.</creator><creator>Greville‐Heygate, Oliver</creator><creator>Constantino‐Casas, Fernando</creator><creator>Williams, David L.</creator><creator>Genain, Marie‐Aude</creator><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-3320-6043</orcidid><orcidid>https://orcid.org/0000-0002-6895-4527</orcidid></search><sort><creationdate>202105</creationdate><title>Multimodality characteristics of multifocal choroid plexus carcinoma with bilateral calvarial defects in a dog</title><author>Hughes, Jonathan R. ; Taylor‐Brown, Frances E. ; Greville‐Heygate, Oliver ; Constantino‐Casas, Fernando ; Williams, David L. ; Genain, Marie‐Aude</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3602-d68a3587bfb98e4e54880f49bbcc2ddc17af1f55e63600adb54db35c315418903</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>brain neoplasia</topic><topic>calvarium</topic><topic>skull defect</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hughes, Jonathan R.</creatorcontrib><creatorcontrib>Taylor‐Brown, Frances E.</creatorcontrib><creatorcontrib>Greville‐Heygate, Oliver</creatorcontrib><creatorcontrib>Constantino‐Casas, Fernando</creatorcontrib><creatorcontrib>Williams, David L.</creatorcontrib><creatorcontrib>Genain, Marie‐Aude</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Veterinary radiology & ultrasound</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hughes, Jonathan R.</au><au>Taylor‐Brown, Frances E.</au><au>Greville‐Heygate, Oliver</au><au>Constantino‐Casas, Fernando</au><au>Williams, David L.</au><au>Genain, Marie‐Aude</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Multimodality characteristics of multifocal choroid plexus carcinoma with bilateral calvarial defects in a dog</atitle><jtitle>Veterinary radiology & ultrasound</jtitle><addtitle>Vet Radiol Ultrasound</addtitle><date>2021-05</date><risdate>2021</risdate><volume>62</volume><issue>3</issue><spage>E20</spage><epage>E25</epage><pages>E20-E25</pages><issn>1058-8183</issn><eissn>1740-8261</eissn><abstract>An 8‐year‐old male intact miniature poodle presented for blindness, obtundation, tetraparesis, and vestibular signs. 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subjects | brain neoplasia calvarium skull defect |
title | Multimodality characteristics of multifocal choroid plexus carcinoma with bilateral calvarial defects in a dog |
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