Association Between Time‐in‐Therapeutic Tacrolimus Range and Early Rejection After Heart Transplant

Background Historically, there is perceived pressure to achieve therapeutic levels of tacrolimus quickly after heart transplant (HT). We evaluated the association between time within therapeutic tacrolimus range and time to therapeutic trough and rejection in the 30 days following HT. Methods This i...

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Veröffentlicht in:	Pharmacotherapy 2019-05, Vol.39 (5), p.609-613
Hauptverfasser:	Baker, William L., Steiger, Samantha, Martin, Spencer, Patel, Nirav, Radojevic, Joseph, Darsaklis, Konstadina, O'Bara, Lynn, Kutzler, Heather, Dougherty, James, Feingold, Andrew, Hammond, Jonathan, Fusco, Daniel, Gluck, Jason A
Format:	Artikel
Sprache:	eng
Schlagworte:	Cohort Studies Drug Administration Schedule Female Graft rejection Graft Rejection - prevention & control Heart Transplantation Histology Historical account Humans Immunosuppression Immunosuppressive Agents - administration & dosage Immunosuppressive Agents - therapeutic use Male Middle Aged rejection Retrospective Studies Tacrolimus Tacrolimus - administration & dosage Tacrolimus - therapeutic use time‐in‐therapeutic range Treatment Outcome
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