The novel gene apnoia regulates Drosophila tracheal tube size

Background Distinct tube size is critical for the function of human tubular organs such as the lung, vascular system, and kidney. Aberrant tube sizes can lead to devastating human illnesses, including polycystic kidney disease. The Drosophila trachea provides a premier genetic system to investigate...

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Veröffentlicht in:	Developmental dynamics 2019-06, Vol.248 (6), p.477-487
Hauptverfasser:	Scholl, Aaron, O'Brien, Michael J., Chandran, Rachana R., Jiang, Lan
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals apn Cell Polarity Cytoplasmic Vesicles - chemistry Cytoplasmic Vesicles - physiology Defects Domains Drosophila Drosophila melanogaster - embryology Drosophila melanogaster - genetics Drosophila Proteins - genetics Drosophila Proteins - physiology Elongation Embryos Gene expression Illnesses Insects Kidney diseases luminal matrix Membrane proteins Membrane Proteins - genetics Membrane Proteins - physiology Morphogenesis - genetics Mutation Organs Polarity Polycystic kidney Trachea Trachea - embryology tracheal Transmembrane domains tube size Tubes Vascular system vesicular trafficking
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