Etoposide phosphate for pediatric orthopedic malignancies after intravenous etoposide hypersensitivity

Background Hypersensitivity reactions to etoposide have been reported and patients have been safely transitioned to etoposide phosphate for continued therapy. However, the safety and efficacy of substituting etoposide phosphate for etoposide has not been well established in pediatric orthopedic mali...

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Veröffentlicht in:	Journal of oncology pharmacy practice 2020-01, Vol.26 (1), p.228-231
Hauptverfasser:	Brooks, Joel P, Azmy, Veronica, Thompson, Alison, Luon, Darren, Prozora, Stephanie D, Price, Christina, Hsu, F Ida
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Bone Neoplasms - drug therapy Desensitization Dexamethasone Diphenhydramine Drug Hypersensitivity - etiology Etoposide Etoposide - adverse effects Etoposide - analogs & derivatives Etoposide - therapeutic use Ewing's sarcoma Health care facilities Humans Hypersensitivity Intravenous administration Male Organophosphorus Compounds - therapeutic use Orthopedics Osteosarcoma Osteosarcoma - drug therapy Patients Pediatrics Phosphate Phosphates Sarcoma Sarcoma, Ewing - drug therapy
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