Development of a multi-institutional registry for children with operative congenital lung malformations

The purpose of this study was to develop a multi-institutional registry to characterize the demographics, management, and outcomes of a contemporary cohort of children undergoing congenital lung malformation (CLM) resection. After central reliance IRB approval, a web-based, secure database was creat...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of pediatric surgery 2020-07, Vol.55 (7), p.1313-1318
Hauptverfasser: Kunisaki, Shaun M., Saito, Jacqueline M., Fallat, Mary E., St. Peter, Shawn D., Lal, Dave R., Johnson, Kevin N., Mon, Rodrigo A., Adams, Cheryl, Aladegbami, Bola, Bence, Christina, Burns, R. Cartland, Corkum, Kristine S., Deans, Katherine J., Downard, Cynthia D., Fraser, Jason D., Gadepalli, Samir K., Helmrath, Michael A., Kabre, Rashmi, Landman, Matthew P., Leys, Charles M., Linden, Allison F., Lopez, Joseph J., Mak, Grace Z., Minneci, Peter C., Rademacher, Brooks L., Shaaban, Aimen, Walker, Sarah K., Wright, Tiffany N., Hirschl, Ronald B.
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 1318
container_issue 7
container_start_page 1313
container_title Journal of pediatric surgery
container_volume 55
creator Kunisaki, Shaun M.
Saito, Jacqueline M.
Fallat, Mary E.
St. Peter, Shawn D.
Lal, Dave R.
Johnson, Kevin N.
Mon, Rodrigo A.
Adams, Cheryl
Aladegbami, Bola
Bence, Christina
Burns, R. Cartland
Corkum, Kristine S.
Deans, Katherine J.
Downard, Cynthia D.
Fraser, Jason D.
Gadepalli, Samir K.
Helmrath, Michael A.
Kabre, Rashmi
Landman, Matthew P.
Leys, Charles M.
Linden, Allison F.
Lopez, Joseph J.
Mak, Grace Z.
Minneci, Peter C.
Rademacher, Brooks L.
Shaaban, Aimen
Walker, Sarah K.
Wright, Tiffany N.
Hirschl, Ronald B.
description The purpose of this study was to develop a multi-institutional registry to characterize the demographics, management, and outcomes of a contemporary cohort of children undergoing congenital lung malformation (CLM) resection. After central reliance IRB approval, a web-based, secure database was created to capture retrospective cohort data on pathologically-confirmed CLMs performed between 2009 and 2015 within a multi-institutional research collaborative. Eleven children's hospitals contributed 506 patients. Among 344 prenatally diagnosed lesions, the congenital pulmonary airway malformation volume ratio was measured in 49.1%, and fetal MRI was performed in 34.3%. One hundred thirty-four (26.7%) children had respiratory symptoms at birth. Fifty-eight (11.6%) underwent neonatal resection, 322 (64.1%) had surgery at 1–12 months, and 122 (24.3%) had operations after 12 months. The median age at resection was 6.7 months (interquartile range, 3.6–11.4). Among 230 elective lobectomies performed in asymptomatic patients, thoracoscopy was successfully utilized in 102 (44.3%), but there was substantial variation across centers. The most common lesions were congenital pulmonary airway malformation (n = 234, 47.3%) and intralobar bronchopulmonary sequestration (n = 106, 21.4%). This multicenter cohort study on operative CLMs highlights marked disease heterogeneity and substantial practice variation in preoperative evaluation and operative management. Future registry studies are planned to help establish evidence-based guidelines to optimize the care of these patients. Level II.
doi_str_mv 10.1016/j.jpedsurg.2019.01.058
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2193623195</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0022346819301125</els_id><sourcerecordid>2193623195</sourcerecordid><originalsourceid>FETCH-LOGICAL-c416t-16d80c816d32a5d2836d7e041f4b760c944eab13cd4ccb1e12b561f1ae4156d03</originalsourceid><addsrcrecordid>eNqFkE1v1DAQhi0EokvhL1Q-cknwxImT3EClfEiVuMDZcuxJ6pVjB9tZ1H-PV9ty5fRKo2fm1TyE3ACrgYH4cKyPG5q0x6VuGIw1g5p1wwtygI5D1THevyQHxpqm4q0YrsiblI6MlTGD1-SKs6Ef-04cyPIZT-jCtqLPNMxU0XV32VbWp2zznm3wytGIi005PtI5RKofrDMRPf1j8wMNG0aV7QmpDn5Bb3Ph3e4XuipX8FWdb6S35NWsXMJ3T3lNfn25-3n7rbr_8fX77af7SrcgcgXCDEwPJXijOtMMXJgeWQtzO_WC6bFtUU3AtWm1ngChmToBMyhsoROG8Wvy_nJ3i-H3jinL1SaNzimPYU-ygZGLhsPYFVRcUB1DShFnuUW7qvgogcmzZHmUz5LlWbJkIIvksnjz1LFPK5p_a89WC_DxAmD59GQxyqQteo3GRtRZmmD_1_EXu_eT6A</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2193623195</pqid></control><display><type>article</type><title>Development of a multi-institutional registry for children with operative congenital lung malformations</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals Complete</source><creator>Kunisaki, Shaun M. ; Saito, Jacqueline M. ; Fallat, Mary E. ; St. Peter, Shawn D. ; Lal, Dave R. ; Johnson, Kevin N. ; Mon, Rodrigo A. ; Adams, Cheryl ; Aladegbami, Bola ; Bence, Christina ; Burns, R. Cartland ; Corkum, Kristine S. ; Deans, Katherine J. ; Downard, Cynthia D. ; Fraser, Jason D. ; Gadepalli, Samir K. ; Helmrath, Michael A. ; Kabre, Rashmi ; Landman, Matthew P. ; Leys, Charles M. ; Linden, Allison F. ; Lopez, Joseph J. ; Mak, Grace Z. ; Minneci, Peter C. ; Rademacher, Brooks L. ; Shaaban, Aimen ; Walker, Sarah K. ; Wright, Tiffany N. ; Hirschl, Ronald B.</creator><creatorcontrib>Kunisaki, Shaun M. ; Saito, Jacqueline M. ; Fallat, Mary E. ; St. Peter, Shawn D. ; Lal, Dave R. ; Johnson, Kevin N. ; Mon, Rodrigo A. ; Adams, Cheryl ; Aladegbami, Bola ; Bence, Christina ; Burns, R. Cartland ; Corkum, Kristine S. ; Deans, Katherine J. ; Downard, Cynthia D. ; Fraser, Jason D. ; Gadepalli, Samir K. ; Helmrath, Michael A. ; Kabre, Rashmi ; Landman, Matthew P. ; Leys, Charles M. ; Linden, Allison F. ; Lopez, Joseph J. ; Mak, Grace Z. ; Minneci, Peter C. ; Rademacher, Brooks L. ; Shaaban, Aimen ; Walker, Sarah K. ; Wright, Tiffany N. ; Hirschl, Ronald B. ; Midwest Pediatric Surgery Consortium</creatorcontrib><description>The purpose of this study was to develop a multi-institutional registry to characterize the demographics, management, and outcomes of a contemporary cohort of children undergoing congenital lung malformation (CLM) resection. After central reliance IRB approval, a web-based, secure database was created to capture retrospective cohort data on pathologically-confirmed CLMs performed between 2009 and 2015 within a multi-institutional research collaborative. Eleven children's hospitals contributed 506 patients. Among 344 prenatally diagnosed lesions, the congenital pulmonary airway malformation volume ratio was measured in 49.1%, and fetal MRI was performed in 34.3%. One hundred thirty-four (26.7%) children had respiratory symptoms at birth. Fifty-eight (11.6%) underwent neonatal resection, 322 (64.1%) had surgery at 1–12 months, and 122 (24.3%) had operations after 12 months. The median age at resection was 6.7 months (interquartile range, 3.6–11.4). Among 230 elective lobectomies performed in asymptomatic patients, thoracoscopy was successfully utilized in 102 (44.3%), but there was substantial variation across centers. The most common lesions were congenital pulmonary airway malformation (n = 234, 47.3%) and intralobar bronchopulmonary sequestration (n = 106, 21.4%). This multicenter cohort study on operative CLMs highlights marked disease heterogeneity and substantial practice variation in preoperative evaluation and operative management. Future registry studies are planned to help establish evidence-based guidelines to optimize the care of these patients. Level II.</description><identifier>ISSN: 0022-3468</identifier><identifier>EISSN: 1531-5037</identifier><identifier>DOI: 10.1016/j.jpedsurg.2019.01.058</identifier><identifier>PMID: 30879756</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Bronchopulmonary sequestration ; Congenital cystic adenomatoid malformation ; Congenital lung malformations ; Congenital pulmonary airway malformation ; Humans ; Infant ; Infant, Newborn ; Lung - abnormalities ; Lung - surgery ; Prenatal Diagnosis ; Registries ; Registry ; Respiratory System Abnormalities - diagnosis ; Respiratory System Abnormalities - epidemiology ; Respiratory System Abnormalities - surgery ; Retrospective Studies</subject><ispartof>Journal of pediatric surgery, 2020-07, Vol.55 (7), p.1313-1318</ispartof><rights>2019 Elsevier Inc.</rights><rights>Copyright © 2019 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c416t-16d80c816d32a5d2836d7e041f4b760c944eab13cd4ccb1e12b561f1ae4156d03</citedby><cites>FETCH-LOGICAL-c416t-16d80c816d32a5d2836d7e041f4b760c944eab13cd4ccb1e12b561f1ae4156d03</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jpedsurg.2019.01.058$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30879756$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kunisaki, Shaun M.</creatorcontrib><creatorcontrib>Saito, Jacqueline M.</creatorcontrib><creatorcontrib>Fallat, Mary E.</creatorcontrib><creatorcontrib>St. Peter, Shawn D.</creatorcontrib><creatorcontrib>Lal, Dave R.</creatorcontrib><creatorcontrib>Johnson, Kevin N.</creatorcontrib><creatorcontrib>Mon, Rodrigo A.</creatorcontrib><creatorcontrib>Adams, Cheryl</creatorcontrib><creatorcontrib>Aladegbami, Bola</creatorcontrib><creatorcontrib>Bence, Christina</creatorcontrib><creatorcontrib>Burns, R. Cartland</creatorcontrib><creatorcontrib>Corkum, Kristine S.</creatorcontrib><creatorcontrib>Deans, Katherine J.</creatorcontrib><creatorcontrib>Downard, Cynthia D.</creatorcontrib><creatorcontrib>Fraser, Jason D.</creatorcontrib><creatorcontrib>Gadepalli, Samir K.</creatorcontrib><creatorcontrib>Helmrath, Michael A.</creatorcontrib><creatorcontrib>Kabre, Rashmi</creatorcontrib><creatorcontrib>Landman, Matthew P.</creatorcontrib><creatorcontrib>Leys, Charles M.</creatorcontrib><creatorcontrib>Linden, Allison F.</creatorcontrib><creatorcontrib>Lopez, Joseph J.</creatorcontrib><creatorcontrib>Mak, Grace Z.</creatorcontrib><creatorcontrib>Minneci, Peter C.</creatorcontrib><creatorcontrib>Rademacher, Brooks L.</creatorcontrib><creatorcontrib>Shaaban, Aimen</creatorcontrib><creatorcontrib>Walker, Sarah K.</creatorcontrib><creatorcontrib>Wright, Tiffany N.</creatorcontrib><creatorcontrib>Hirschl, Ronald B.</creatorcontrib><creatorcontrib>Midwest Pediatric Surgery Consortium</creatorcontrib><title>Development of a multi-institutional registry for children with operative congenital lung malformations</title><title>Journal of pediatric surgery</title><addtitle>J Pediatr Surg</addtitle><description>The purpose of this study was to develop a multi-institutional registry to characterize the demographics, management, and outcomes of a contemporary cohort of children undergoing congenital lung malformation (CLM) resection. After central reliance IRB approval, a web-based, secure database was created to capture retrospective cohort data on pathologically-confirmed CLMs performed between 2009 and 2015 within a multi-institutional research collaborative. Eleven children's hospitals contributed 506 patients. Among 344 prenatally diagnosed lesions, the congenital pulmonary airway malformation volume ratio was measured in 49.1%, and fetal MRI was performed in 34.3%. One hundred thirty-four (26.7%) children had respiratory symptoms at birth. Fifty-eight (11.6%) underwent neonatal resection, 322 (64.1%) had surgery at 1–12 months, and 122 (24.3%) had operations after 12 months. The median age at resection was 6.7 months (interquartile range, 3.6–11.4). Among 230 elective lobectomies performed in asymptomatic patients, thoracoscopy was successfully utilized in 102 (44.3%), but there was substantial variation across centers. The most common lesions were congenital pulmonary airway malformation (n = 234, 47.3%) and intralobar bronchopulmonary sequestration (n = 106, 21.4%). This multicenter cohort study on operative CLMs highlights marked disease heterogeneity and substantial practice variation in preoperative evaluation and operative management. Future registry studies are planned to help establish evidence-based guidelines to optimize the care of these patients. Level II.</description><subject>Bronchopulmonary sequestration</subject><subject>Congenital cystic adenomatoid malformation</subject><subject>Congenital lung malformations</subject><subject>Congenital pulmonary airway malformation</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Lung - abnormalities</subject><subject>Lung - surgery</subject><subject>Prenatal Diagnosis</subject><subject>Registries</subject><subject>Registry</subject><subject>Respiratory System Abnormalities - diagnosis</subject><subject>Respiratory System Abnormalities - epidemiology</subject><subject>Respiratory System Abnormalities - surgery</subject><subject>Retrospective Studies</subject><issn>0022-3468</issn><issn>1531-5037</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1v1DAQhi0EokvhL1Q-cknwxImT3EClfEiVuMDZcuxJ6pVjB9tZ1H-PV9ty5fRKo2fm1TyE3ACrgYH4cKyPG5q0x6VuGIw1g5p1wwtygI5D1THevyQHxpqm4q0YrsiblI6MlTGD1-SKs6Ef-04cyPIZT-jCtqLPNMxU0XV32VbWp2zznm3wytGIi005PtI5RKofrDMRPf1j8wMNG0aV7QmpDn5Bb3Ph3e4XuipX8FWdb6S35NWsXMJ3T3lNfn25-3n7rbr_8fX77af7SrcgcgXCDEwPJXijOtMMXJgeWQtzO_WC6bFtUU3AtWm1ngChmToBMyhsoROG8Wvy_nJ3i-H3jinL1SaNzimPYU-ygZGLhsPYFVRcUB1DShFnuUW7qvgogcmzZHmUz5LlWbJkIIvksnjz1LFPK5p_a89WC_DxAmD59GQxyqQteo3GRtRZmmD_1_EXu_eT6A</recordid><startdate>202007</startdate><enddate>202007</enddate><creator>Kunisaki, Shaun M.</creator><creator>Saito, Jacqueline M.</creator><creator>Fallat, Mary E.</creator><creator>St. Peter, Shawn D.</creator><creator>Lal, Dave R.</creator><creator>Johnson, Kevin N.</creator><creator>Mon, Rodrigo A.</creator><creator>Adams, Cheryl</creator><creator>Aladegbami, Bola</creator><creator>Bence, Christina</creator><creator>Burns, R. Cartland</creator><creator>Corkum, Kristine S.</creator><creator>Deans, Katherine J.</creator><creator>Downard, Cynthia D.</creator><creator>Fraser, Jason D.</creator><creator>Gadepalli, Samir K.</creator><creator>Helmrath, Michael A.</creator><creator>Kabre, Rashmi</creator><creator>Landman, Matthew P.</creator><creator>Leys, Charles M.</creator><creator>Linden, Allison F.</creator><creator>Lopez, Joseph J.</creator><creator>Mak, Grace Z.</creator><creator>Minneci, Peter C.</creator><creator>Rademacher, Brooks L.</creator><creator>Shaaban, Aimen</creator><creator>Walker, Sarah K.</creator><creator>Wright, Tiffany N.</creator><creator>Hirschl, Ronald B.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>202007</creationdate><title>Development of a multi-institutional registry for children with operative congenital lung malformations</title><author>Kunisaki, Shaun M. ; Saito, Jacqueline M. ; Fallat, Mary E. ; St. Peter, Shawn D. ; Lal, Dave R. ; Johnson, Kevin N. ; Mon, Rodrigo A. ; Adams, Cheryl ; Aladegbami, Bola ; Bence, Christina ; Burns, R. Cartland ; Corkum, Kristine S. ; Deans, Katherine J. ; Downard, Cynthia D. ; Fraser, Jason D. ; Gadepalli, Samir K. ; Helmrath, Michael A. ; Kabre, Rashmi ; Landman, Matthew P. ; Leys, Charles M. ; Linden, Allison F. ; Lopez, Joseph J. ; Mak, Grace Z. ; Minneci, Peter C. ; Rademacher, Brooks L. ; Shaaban, Aimen ; Walker, Sarah K. ; Wright, Tiffany N. ; Hirschl, Ronald B.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c416t-16d80c816d32a5d2836d7e041f4b760c944eab13cd4ccb1e12b561f1ae4156d03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Bronchopulmonary sequestration</topic><topic>Congenital cystic adenomatoid malformation</topic><topic>Congenital lung malformations</topic><topic>Congenital pulmonary airway malformation</topic><topic>Humans</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Lung - abnormalities</topic><topic>Lung - surgery</topic><topic>Prenatal Diagnosis</topic><topic>Registries</topic><topic>Registry</topic><topic>Respiratory System Abnormalities - diagnosis</topic><topic>Respiratory System Abnormalities - epidemiology</topic><topic>Respiratory System Abnormalities - surgery</topic><topic>Retrospective Studies</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kunisaki, Shaun M.</creatorcontrib><creatorcontrib>Saito, Jacqueline M.</creatorcontrib><creatorcontrib>Fallat, Mary E.</creatorcontrib><creatorcontrib>St. Peter, Shawn D.</creatorcontrib><creatorcontrib>Lal, Dave R.</creatorcontrib><creatorcontrib>Johnson, Kevin N.</creatorcontrib><creatorcontrib>Mon, Rodrigo A.</creatorcontrib><creatorcontrib>Adams, Cheryl</creatorcontrib><creatorcontrib>Aladegbami, Bola</creatorcontrib><creatorcontrib>Bence, Christina</creatorcontrib><creatorcontrib>Burns, R. Cartland</creatorcontrib><creatorcontrib>Corkum, Kristine S.</creatorcontrib><creatorcontrib>Deans, Katherine J.</creatorcontrib><creatorcontrib>Downard, Cynthia D.</creatorcontrib><creatorcontrib>Fraser, Jason D.</creatorcontrib><creatorcontrib>Gadepalli, Samir K.</creatorcontrib><creatorcontrib>Helmrath, Michael A.</creatorcontrib><creatorcontrib>Kabre, Rashmi</creatorcontrib><creatorcontrib>Landman, Matthew P.</creatorcontrib><creatorcontrib>Leys, Charles M.</creatorcontrib><creatorcontrib>Linden, Allison F.</creatorcontrib><creatorcontrib>Lopez, Joseph J.</creatorcontrib><creatorcontrib>Mak, Grace Z.</creatorcontrib><creatorcontrib>Minneci, Peter C.</creatorcontrib><creatorcontrib>Rademacher, Brooks L.</creatorcontrib><creatorcontrib>Shaaban, Aimen</creatorcontrib><creatorcontrib>Walker, Sarah K.</creatorcontrib><creatorcontrib>Wright, Tiffany N.</creatorcontrib><creatorcontrib>Hirschl, Ronald B.</creatorcontrib><creatorcontrib>Midwest Pediatric Surgery Consortium</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of pediatric surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kunisaki, Shaun M.</au><au>Saito, Jacqueline M.</au><au>Fallat, Mary E.</au><au>St. Peter, Shawn D.</au><au>Lal, Dave R.</au><au>Johnson, Kevin N.</au><au>Mon, Rodrigo A.</au><au>Adams, Cheryl</au><au>Aladegbami, Bola</au><au>Bence, Christina</au><au>Burns, R. Cartland</au><au>Corkum, Kristine S.</au><au>Deans, Katherine J.</au><au>Downard, Cynthia D.</au><au>Fraser, Jason D.</au><au>Gadepalli, Samir K.</au><au>Helmrath, Michael A.</au><au>Kabre, Rashmi</au><au>Landman, Matthew P.</au><au>Leys, Charles M.</au><au>Linden, Allison F.</au><au>Lopez, Joseph J.</au><au>Mak, Grace Z.</au><au>Minneci, Peter C.</au><au>Rademacher, Brooks L.</au><au>Shaaban, Aimen</au><au>Walker, Sarah K.</au><au>Wright, Tiffany N.</au><au>Hirschl, Ronald B.</au><aucorp>Midwest Pediatric Surgery Consortium</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Development of a multi-institutional registry for children with operative congenital lung malformations</atitle><jtitle>Journal of pediatric surgery</jtitle><addtitle>J Pediatr Surg</addtitle><date>2020-07</date><risdate>2020</risdate><volume>55</volume><issue>7</issue><spage>1313</spage><epage>1318</epage><pages>1313-1318</pages><issn>0022-3468</issn><eissn>1531-5037</eissn><abstract>The purpose of this study was to develop a multi-institutional registry to characterize the demographics, management, and outcomes of a contemporary cohort of children undergoing congenital lung malformation (CLM) resection. After central reliance IRB approval, a web-based, secure database was created to capture retrospective cohort data on pathologically-confirmed CLMs performed between 2009 and 2015 within a multi-institutional research collaborative. Eleven children's hospitals contributed 506 patients. Among 344 prenatally diagnosed lesions, the congenital pulmonary airway malformation volume ratio was measured in 49.1%, and fetal MRI was performed in 34.3%. One hundred thirty-four (26.7%) children had respiratory symptoms at birth. Fifty-eight (11.6%) underwent neonatal resection, 322 (64.1%) had surgery at 1–12 months, and 122 (24.3%) had operations after 12 months. The median age at resection was 6.7 months (interquartile range, 3.6–11.4). Among 230 elective lobectomies performed in asymptomatic patients, thoracoscopy was successfully utilized in 102 (44.3%), but there was substantial variation across centers. The most common lesions were congenital pulmonary airway malformation (n = 234, 47.3%) and intralobar bronchopulmonary sequestration (n = 106, 21.4%). This multicenter cohort study on operative CLMs highlights marked disease heterogeneity and substantial practice variation in preoperative evaluation and operative management. Future registry studies are planned to help establish evidence-based guidelines to optimize the care of these patients. Level II.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>30879756</pmid><doi>10.1016/j.jpedsurg.2019.01.058</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0022-3468
ispartof Journal of pediatric surgery, 2020-07, Vol.55 (7), p.1313-1318
issn 0022-3468
1531-5037
language eng
recordid cdi_proquest_miscellaneous_2193623195
source MEDLINE; Elsevier ScienceDirect Journals Complete
subjects Bronchopulmonary sequestration
Congenital cystic adenomatoid malformation
Congenital lung malformations
Congenital pulmonary airway malformation
Humans
Infant
Infant, Newborn
Lung - abnormalities
Lung - surgery
Prenatal Diagnosis
Registries
Registry
Respiratory System Abnormalities - diagnosis
Respiratory System Abnormalities - epidemiology
Respiratory System Abnormalities - surgery
Retrospective Studies
title Development of a multi-institutional registry for children with operative congenital lung malformations
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-24T07%3A28%3A09IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Development%20of%20a%20multi-institutional%20registry%20for%20children%20with%20operative%20congenital%20lung%20malformations&rft.jtitle=Journal%20of%20pediatric%20surgery&rft.au=Kunisaki,%20Shaun%20M.&rft.aucorp=Midwest%20Pediatric%20Surgery%20Consortium&rft.date=2020-07&rft.volume=55&rft.issue=7&rft.spage=1313&rft.epage=1318&rft.pages=1313-1318&rft.issn=0022-3468&rft.eissn=1531-5037&rft_id=info:doi/10.1016/j.jpedsurg.2019.01.058&rft_dat=%3Cproquest_cross%3E2193623195%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2193623195&rft_id=info:pmid/30879756&rft_els_id=S0022346819301125&rfr_iscdi=true