Outcomes following mycophenolate mofetil versus cyclophosphamide induction treatment for proliferative juvenile-onset lupus nephritis

Background Juvenile-onset systemic lupus erythematosus (JSLE) is more severe than adult-onset disease, including more lupus nephritis (LN). Despite differences in phenotype/pathogenesis, treatment is based upon adult trials. This study aimed to compare treatment response, damage accrual, time to ina...

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Veröffentlicht in:	Lupus 2019-04, Vol.28 (5), p.613-620
Hauptverfasser:	Smith, EMD, Al-Abadi, E, Armon, K, Bailey, K, Ciurtin, C, Davidson, J, Gardner-Medwin, J, Haslam, K, Hawley, D, Leahy, A, Leone, V, McErlane, F, Mewar, D, Modgil, G, Moots, R, Pilkington, C, Ramanan, A, Rangaraj, S, Riley, P, Sridhar, A, Wilkinson, N, Beresford, M W, Hedrich, C M
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-DNA antibodies Biopsy Clinical trials Creatinine Cyclophosphamide Intravenous administration Kidneys Lupus Lupus nephritis Mycophenolate mofetil Mycophenolic acid Nephritis Phenotypes Statistical analysis Systemic lupus erythematosus Urine
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