A Transcriptionally Distinct CXCL13 + CD103 + CD8 + T-cell Population Is Associated with B-cell Recruitment and Neoantigen Load in Human Cancer

The chemokine CXCL13 mediates recruitment of B cells to tumors and is essential for the formation of tertiary lymphoid structures (TLSs). TLSs are thought to support antitumor immunity and are associated with improved prognosis. However, it remains unknown whether TLSs are formed in response to the...

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Veröffentlicht in:	Cancer immunology research 2019-05, Vol.7 (5), p.784-796
Hauptverfasser:	Workel, Hagma H, Lubbers, Joyce M, Arnold, Roland, Prins, Thalina M, van der Vlies, Pieter, de Lange, Kim, Bosse, Tjalling, van Gool, Inge C, Eggink, Florine A, Wouters, Maartje C A, Komdeur, Fenne L, van der Slikke, Elisabeth C, Creutzberg, Carien L, Kol, Arjan, Plat, Annechien, Glaire, Mark, Church, David N, Nijman, Hans W, de Bruyn, Marco
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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