Science and health for all children with cancer

Each year ~429,000 children and adolescents aged 0 to 19 years are expected to develop cancer. Five-year survival rates exceed 80% for the 45,000 children with cancer in high-income countries (HICs) but are less than 30% for the 384,000 children in lower-middle-income countries (LMICs). Improved sur...

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Veröffentlicht in:Science (American Association for the Advancement of Science) 2019-03, Vol.363 (6432), p.1182-1186
Hauptverfasser: Lam, Catherine G., Howard, Scott C., Bouffet, Eric, Pritchard-Jones, Kathy
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container_issue 6432
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container_title Science (American Association for the Advancement of Science)
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creator Lam, Catherine G.
Howard, Scott C.
Bouffet, Eric
Pritchard-Jones, Kathy
description Each year ~429,000 children and adolescents aged 0 to 19 years are expected to develop cancer. Five-year survival rates exceed 80% for the 45,000 children with cancer in high-income countries (HICs) but are less than 30% for the 384,000 children in lower-middle-income countries (LMICs). Improved survival rates in HICs have been achieved through multidisciplinary care and research, with treatment regimens using mostly generic medicines and optimized risk stratification. Children’s outcomes in LMICs can be improved through global collaborative partnerships that help local leaders adapt effective treatments to local resources and clinical needs, as well as address common problems such as delayed diagnosis and treatment abandonment. Together, these approaches may bring within reach the global survival target recently set by the World Health Organization: 60% survival for all children with cancer by 2030.
doi_str_mv 10.1126/science.aaw4892
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subjects Abandonment
Adolescent
Adolescents
Adult
Cancer
Child
Child, Preschool
Children
Delayed Diagnosis - adverse effects
Developed Countries - statistics & numerical data
Developing Countries - statistics & numerical data
Drug Development
Global Health
Health Resources
Health Services Accessibility
Humans
Incidence
Income
Infant
Infant, Newborn
Neoplasms - diagnosis
Neoplasms - mortality
Neoplasms - therapy
Partnerships
REVIEW
Survival
World Health Organization
Young Adult
title Science and health for all children with cancer
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