Science and health for all children with cancer
Each year ~429,000 children and adolescents aged 0 to 19 years are expected to develop cancer. Five-year survival rates exceed 80% for the 45,000 children with cancer in high-income countries (HICs) but are less than 30% for the 384,000 children in lower-middle-income countries (LMICs). Improved sur...
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Veröffentlicht in: | Science (American Association for the Advancement of Science) 2019-03, Vol.363 (6432), p.1182-1186 |
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creator | Lam, Catherine G. Howard, Scott C. Bouffet, Eric Pritchard-Jones, Kathy |
description | Each year ~429,000 children and adolescents aged 0 to 19 years are expected to develop cancer. Five-year survival rates exceed 80% for the 45,000 children with cancer in high-income countries (HICs) but are less than 30% for the 384,000 children in lower-middle-income countries (LMICs). Improved survival rates in HICs have been achieved through multidisciplinary care and research, with treatment regimens using mostly generic medicines and optimized risk stratification. Children’s outcomes in LMICs can be improved through global collaborative partnerships that help local leaders adapt effective treatments to local resources and clinical needs, as well as address common problems such as delayed diagnosis and treatment abandonment. Together, these approaches may bring within reach the global survival target recently set by the World Health Organization: 60% survival for all children with cancer by 2030. |
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Five-year survival rates exceed 80% for the 45,000 children with cancer in high-income countries (HICs) but are less than 30% for the 384,000 children in lower-middle-income countries (LMICs). Improved survival rates in HICs have been achieved through multidisciplinary care and research, with treatment regimens using mostly generic medicines and optimized risk stratification. Children’s outcomes in LMICs can be improved through global collaborative partnerships that help local leaders adapt effective treatments to local resources and clinical needs, as well as address common problems such as delayed diagnosis and treatment abandonment. Together, these approaches may bring within reach the global survival target recently set by the World Health Organization: 60% survival for all children with cancer by 2030.</description><identifier>ISSN: 0036-8075</identifier><identifier>EISSN: 1095-9203</identifier><identifier>DOI: 10.1126/science.aaw4892</identifier><identifier>PMID: 30872518</identifier><language>eng</language><publisher>United States: American Association for the Advancement of Science</publisher><subject>Abandonment ; Adolescent ; Adolescents ; Adult ; Cancer ; Child ; Child, Preschool ; Children ; Delayed Diagnosis - adverse effects ; Developed Countries - statistics & numerical data ; Developing Countries - statistics & numerical data ; Drug Development ; Global Health ; Health Resources ; Health Services Accessibility ; Humans ; Incidence ; Income ; Infant ; Infant, Newborn ; Neoplasms - diagnosis ; Neoplasms - mortality ; Neoplasms - therapy ; Partnerships ; REVIEW ; Survival ; World Health Organization ; Young Adult</subject><ispartof>Science (American Association for the Advancement of Science), 2019-03, Vol.363 (6432), p.1182-1186</ispartof><rights>Copyright © 2019, American Association for the Advancement of Science.</rights><rights>Copyright © 2019, American Association for the Advancement of Science</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c388t-19f11e3e9f7584425d3f55920bc47a293b0c087c31f8709c12acc6d2c8ca428e3</citedby><cites>FETCH-LOGICAL-c388t-19f11e3e9f7584425d3f55920bc47a293b0c087c31f8709c12acc6d2c8ca428e3</cites><orcidid>0000-0003-2244-1686 ; 0000-0002-2384-9475 ; 0000-0003-1363-5331</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,2871,2872,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30872518$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lam, Catherine G.</creatorcontrib><creatorcontrib>Howard, Scott C.</creatorcontrib><creatorcontrib>Bouffet, Eric</creatorcontrib><creatorcontrib>Pritchard-Jones, Kathy</creatorcontrib><title>Science and health for all children with cancer</title><title>Science (American Association for the Advancement of Science)</title><addtitle>Science</addtitle><description>Each year ~429,000 children and adolescents aged 0 to 19 years are expected to develop cancer. Five-year survival rates exceed 80% for the 45,000 children with cancer in high-income countries (HICs) but are less than 30% for the 384,000 children in lower-middle-income countries (LMICs). Improved survival rates in HICs have been achieved through multidisciplinary care and research, with treatment regimens using mostly generic medicines and optimized risk stratification. Children’s outcomes in LMICs can be improved through global collaborative partnerships that help local leaders adapt effective treatments to local resources and clinical needs, as well as address common problems such as delayed diagnosis and treatment abandonment. 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subjects | Abandonment Adolescent Adolescents Adult Cancer Child Child, Preschool Children Delayed Diagnosis - adverse effects Developed Countries - statistics & numerical data Developing Countries - statistics & numerical data Drug Development Global Health Health Resources Health Services Accessibility Humans Incidence Income Infant Infant, Newborn Neoplasms - diagnosis Neoplasms - mortality Neoplasms - therapy Partnerships REVIEW Survival World Health Organization Young Adult |
title | Science and health for all children with cancer |
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