Modulation of Cav2.3 channels by unconjugated bilirubin (UCB) – Candidate mechanism for UCB-induced neuromodulation and neurotoxicity

Elevated levels of unbound unconjugated bilirubin (UCB) can lead to bilirubin encephalopathy and kernicterus. In spite of a large number of studies demonstrating UCB-induced changes in central neurotransmission, it is still unclear whether these effects involve alterations in the function of specifi...

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Veröffentlicht in:	Molecular and cellular neuroscience 2019-04, Vol.96, p.35-46
Hauptverfasser:	Albanna, Walid, Lüke, Jan Niklas, Schubert, Gerrit Alexander, Dibué-Adjei, Maxine, Kotliar, Konstantin, Hescheler, Jürgen, Clusmann, Hans, Steiger, Hans-Jakob, Hänggi, Daniel, Kamp, Marcel A., Schneider, Toni, Neumaier, Felix
Format:	Artikel
Sprache:	eng
Schlagworte:	Hemoglobin metabolism Jaundice Membrane lipid perturbation Murine electroretinogram Photo-sensitization UCB:albumin molar ratio
Online-Zugang:	Volltext
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