Development of Radioiodinated Benzofuran Derivatives for in Vivo Imaging of Prion Deposits in the Brain

Prion diseases are fatal neurodegenerative disorders associated with the deposition of abnormal prion protein aggregates (PrPSc) in the brain tissue. Here, we report the development of 125I-labeled iodobenzofuran (IBF) derivatives as single photon emission computed tomography (SPECT) imaging probes...

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Veröffentlicht in:	ACS infectious diseases 2019-12, Vol.5 (12), p.2003-2013
Hauptverfasser:	Fuchigami, Takeshi, Kawasaki, Masao, Koyama, Ryusuke, Nakaie, Mari, Nakagaki, Takehiro, Sano, Kazunori, Atarashi, Ryuichiro, Yoshida, Sakura, Haratake, Mamoru, Ono, Masahiro, Nishida, Noriyuki, Nakayama, Morio
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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