Contractile Effects of Serotonin (5-HT) in the Rat Cauda Epididymis: Expression and Functional Characterization of 5-HT Receptors

Serotonin [5-hydroxytryptamine (5-HT)] exerts multiple central and peripheral functions. High concentrations of 5-HT have been found in the epididymis, a ductal organ that plays pivotal roles in sperm transport and maturation. The contraction of the epididymal smooth muscle is essential for sperm tr...

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Veröffentlicht in:	The Journal of pharmacology and experimental therapeutics 2019-04, Vol.369 (1), p.98-106
Hauptverfasser:	Mueller, Andre, Kiguti, Luiz R. A, Silva, Erick J. R, Pupo, André S
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Dose-Response Relationship, Drug Epididymis - drug effects Epididymis - physiology Gene Expression Regulation - drug effects Male Muscle Contraction - drug effects Muscle, Smooth - drug effects Muscle, Smooth - physiology Protein Transport - drug effects Rats Rats, Wistar Receptors, Adrenergic - metabolism Receptors, Adrenergic, alpha-1 - metabolism Receptors, Serotonin - metabolism Serotonin - pharmacology
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