SIRT1 promotes GLUT1 expression and bladder cancer progression via regulation of glucose uptake

Bladder cancer (BC) is one of the most common tumors. Metabolic reprogramming is a feature of neoplasia and tumor growth. Understanding the metabolic alterations in bladder cancer may provide new directions for bladder cancer treatment. Sirtuin 1 (SIRT1) is a lysine deacetylase of multiple targets i...

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Veröffentlicht in:	Human cell : official journal of Human Cell Research Society 2019-04, Vol.32 (2), p.193-201
Hauptverfasser:	Chen, Jia, Cao, Lin, Li, Zhiqiu, Li, Yuanwei
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomedical and Life Sciences Bladder cancer Cell Biology Cell growth Cell Line, Tumor Cell Proliferation Disease Progression Gene Expression - genetics Glucose Glucose - metabolism Glucose Transporter Type 1 - genetics Glucose Transporter Type 1 - metabolism Glycolysis Glycolysis - genetics Glycolysis - physiology Gynecology Humans Life Sciences Lysine Metabolism Oncology Pancreatic cancer Phenotypes Reproductive Medicine Research Article SIRT1 protein Sirtuin 1 - genetics Sirtuin 1 - physiology Stem Cells Surgery Transcription Tumors Up-Regulation Urinary Bladder Neoplasms - genetics Urinary Bladder Neoplasms - metabolism Urinary Bladder Neoplasms - pathology
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