Radical Surgery or Watchful Waiting in Prostate Cancer

Radical Surgery or Watchful Waiting in Prostate Cancer

To the Editor: Bill-Axelson et al. (Dec. 13 issue) 1 report that at a median follow-up of 23.6 years, radical prostatectomy prolonged overall survival among men with localized prostate cancer, as compared with “watchful waiting.” Using a Cox proportional-hazards model, the investigators calculated a...

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Veröffentlicht in:The New England journal of medicine 2019-03, Vol.380 (11), p.1083-1084
Hauptverfasser: Yang, Zhao, McCaw, Zachary R, Yin, Guosheng, Charkes, N. David, Bill-Axelson, Anna, Holmberg, Lars, Garmo, Hans
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Sprache:eng
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Prostate cancer
Prostatectomy
Surgery
Survival
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container_end_page 1084
container_issue 11
container_start_page 1083
container_title The New England journal of medicine
container_volume 380
creator Yang, Zhao
McCaw, Zachary R
Yin, Guosheng
Charkes, N. David
Bill-Axelson, Anna
Holmberg, Lars
Garmo, Hans
description To the Editor: Bill-Axelson et al. (Dec. 13 issue) 1 report that at a median follow-up of 23.6 years, radical prostatectomy prolonged overall survival among men with localized prostate cancer, as compared with “watchful waiting.” Using a Cox proportional-hazards model, the investigators calculated a hazard ratio for death for prostatectomy versus watchful waiting of 0.55 (95% confidence interval [CI], 0.41 to 0.74]), which they reported as a relative risk. At 23 years, they found that prostatectomy extended the men’s lives by a mean of 2.9 years. However, the 23-year residual mean survival time was defined as the average remaining survival time . . .
doi_str_mv 10.1056/NEJMc1900410
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subjects Prostate cancer
Prostatectomy
Surgery
Survival
title Radical Surgery or Watchful Waiting in Prostate Cancer
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