Phaeohyphomycosis caused by Medicopsis romeroi in solid organ transplant recipients: Report of two cases and comprehensive review of the literature

Medicopsis romeroi is a melanized coelomycetous fungus, mainly found in tropical and subtropical regions and an uncommon cause of infection in solid organ transplant (SOT) recipients. We describe two cases of SOT recipients diagnosed with phaeohyphomycosis due to M romeroi and provide a comprehensiv...

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Veröffentlicht in:Transplant infectious disease 2019-06, Vol.21 (3), p.e13072-n/a
Hauptverfasser: Los‐Arcos, Ibai, Royuela, Meritxell, Martín‐Gómez, M. Teresa, Alastruey‐Izquierdo, Ana, Sellarès, Joana, Perelló, Manel, Castells, Lluís, Dopazo, Cristina, Gavaldà, Joan, Len, Oscar
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container_issue 3
container_start_page e13072
container_title Transplant infectious disease
container_volume 21
creator Los‐Arcos, Ibai
Royuela, Meritxell
Martín‐Gómez, M. Teresa
Alastruey‐Izquierdo, Ana
Sellarès, Joana
Perelló, Manel
Castells, Lluís
Dopazo, Cristina
Gavaldà, Joan
Len, Oscar
description Medicopsis romeroi is a melanized coelomycetous fungus, mainly found in tropical and subtropical regions and an uncommon cause of infection in solid organ transplant (SOT) recipients. We describe two cases of SOT recipients diagnosed with phaeohyphomycosis due to M romeroi and provide a comprehensive literature review. These infections should be considered in patients native to tropical countries with a localized skin and soft tissue infection. Sequencing is needed for accurate identification of uncommon melanized fungi. Surgical treatment is recommended to cure the infection and co‐adjunctive oral antifungals should be considered.
doi_str_mv 10.1111/tid.13072
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source MEDLINE; Wiley Online Library Journals Frontfile Complete
subjects Aged
Antifungal agents
Antifungal Agents - pharmacology
Antifungal Agents - therapeutic use
Ascomycota - drug effects
Ascomycota - pathogenicity
Debridement
dematiaceous fungi
Female
Fungi
Health risk assessment
Humans
Infections
Literature reviews
Male
melanized fungi
Microbial Sensitivity Tests
Middle Aged
Organ Transplantation - adverse effects
Phaeohyphomycosis
Phaeohyphomycosis - diagnosis
Phaeohyphomycosis - drug therapy
posaconazole
Retrospective Studies
Skin
Skin - microbiology
Soft tissues
solid organ transplantation
Transplant Recipients
Tropical Climate
voriconazole
title Phaeohyphomycosis caused by Medicopsis romeroi in solid organ transplant recipients: Report of two cases and comprehensive review of the literature
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