LRE-Finder, a Web tool for detection of the 23S rRNA mutations and the optrA, cfr, cfr(B) and poxtA genes encoding linezolid resistance in enterococci from whole-genome sequences

In enterococci, resistance to linezolid is often mediated by mutations in the V domain of the 23S rRNA gene (G2576T or G2505A). Furthermore, four genes [optrA, cfr, cfr(B) and poxtA] encode linezolid resistance in enterococci. We aimed to develop a Web tool for detection of the two mutations and the...

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Veröffentlicht in:	Journal of antimicrobial chemotherapy 2019-06, Vol.74 (6), p.1473-1476
Hauptverfasser:	Hasman, Henrik, Clausen, Philip T L C, Kaya, Hülya, Hansen, Frank, Knudsen, Jenny Dahl, Wang, Mikala, Holzknecht, Barbara Juliane, Samulioniené, Jurgita, Røder, Bent L, Frimodt-Møller, Niels, Lund, Ole, Hammerum, Anette M
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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