Transplacental exposure to carcinogens and risks to children: evidence from biomarker studies and the utility of omic profiling

The factors underlying the increasing rates and the geographic variation of childhood cancers are largely unknown. Epidemiological studies provide limited evidence for a possible role in the etiology of certain types of childhood cancer of the exposure of pregnant women to environmental carcinogens...

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Veröffentlicht in:	Archives of toxicology 2019-04, Vol.93 (4), p.833-857
Hauptverfasser:	Botsivali, Maria, Kyrtopoulos, Soterios A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adults Biomarkers Biomarkers - blood Biomedical and Life Sciences Biomedicine Cancer Carcinogens Carcinogens, Environmental - analysis Carcinogens, Environmental - pharmacokinetics Carcinogens, Environmental - toxicity Child Children Ecological risk assessment Environmental Exposure - adverse effects Environmental Exposure - analysis Environmental Health Epidemiology Etiology Exposure Female Fetal Blood - chemistry Fetal Development - drug effects Fetuses Genotoxicity Health risk assessment Health risks Humans Infant Maternal-Fetal Exchange Neoplasms - blood Neoplasms - chemically induced Neoplasms - epidemiology Occupational Medicine/Industrial Medicine Pesticides Pharmacology/Toxicology Population studies Pregnancy Prenatal Exposure Delayed Effects - blood Prenatal Exposure Delayed Effects - chemically induced Prenatal Exposure Delayed Effects - epidemiology Proteomics - methods Review Article Risk Smoke Tobacco
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