Characterisation of genes differentially expressed in macrophages by virulent and attenuated Mycobacterium tuberculosis through RNA-Seq analysis

Tuberculosis (TB) remains a global healthcare issue. Understanding the host-pathogen interactions in TB is vital to develop strategies and therapeutic tools for the control of Mycobacterium tuberculosis (Mtb). In this study, transcriptome analyses of macrophages infected with either the virulent Mtb...

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Veröffentlicht in:	Scientific reports 2019-03, Vol.9 (1), p.4027-4027, Article 4027
Hauptverfasser:	Lee, Junghwan, Lee, Sung-Gwon, Kim, Kee K, Lim, Yun-Ji, Choi, Ji-Ae, Cho, Soo-Na, Park, Chungoo, Song, Chang-Hwa
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Transport Systems, Basic - physiology Animals Cells, Cultured Host-Pathogen Interactions Macrophages - metabolism Macrophages - microbiology Macrophages - pathology Mice, Inbred C57BL Mycobacterium tuberculosis - pathogenicity Mycobacterium tuberculosis - physiology RNA-Seq - methods Tuberculosis - immunology Tuberculosis - microbiology Virulence
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