NAD-biosynthetic pathways regulate innate immunity
Recent studies indicate that macrophages utilize NAD + -biosynthetic pathways to control inflammation and cell survival during the immune response and aging.
Gespeichert in:
| Veröffentlicht in: | Nature immunology 2019-04, Vol.20 (4), p.380-382 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 382 |
|---|---|
| container_issue | 4 |
| container_start_page | 380 |
| container_title | Nature immunology |
| container_volume | 20 |
| creator | Billingham, Leah K. Chandel, Navdeep S. |
| description | Recent studies indicate that macrophages utilize NAD
+
-biosynthetic pathways to control inflammation and cell survival during the immune response and aging. |
| doi_str_mv | 10.1038/s41590-019-0353-x |
| format | Article |
| fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_2190491654</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A579742265</galeid><sourcerecordid>A579742265</sourcerecordid><originalsourceid>FETCH-LOGICAL-c501t-f02adcd25c9aacb237e018acc6671e1b3339867169e38e781c577ff735fd168f3</originalsourceid><addsrcrecordid>eNp9kUtvEzEUhS1ERUvhB7BBkdiUxRRfe_xaRqWFShVIPNaW47FTVzOeYHtE8u_rkJIqCJAX98r-zvU9Ogi9AnwOmMp3uQWmcINBNZgy2qyfoBNgRDVEAX-677E8Rs9zvsMYWsHbZ-iYYskkJ3CCyKf5-2YRxryJ5daVYGcrU25_mk2eJbecelPcLMT4qwzDFEPZvEBH3vTZvXyop-j71eW3i4_NzecP1xfzm8YyDKXxmJjOdoRZZYxdECocBmms5VyAgwWlVMnacuWodEKCZUJ4LyjzHXDp6Sk6281dpfHH5HLRQ8jW9b2JbpyyJqBwW42ytqJv_kDvxinFup0mrWAYC6DqvxQoRrhgdak9tTS90yH6sSRjt1_rORNKtIRwVqnzv1D1dG4IdozOh3p_IHh7IKhMceuyNFPO-vrrl0MWdqxNY87Jeb1KYTBpowHrbfJ6l7yuyett8npdNa8fzE2LwXV7xe-oK0B2QK5PcenSo_t_T70HLwe0eg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2195267533</pqid></control><display><type>article</type><title>NAD-biosynthetic pathways regulate innate immunity</title><source>MEDLINE</source><source>Nature</source><source>Alma/SFX Local Collection</source><creator>Billingham, Leah K. ; Chandel, Navdeep S.</creator><creatorcontrib>Billingham, Leah K. ; Chandel, Navdeep S.</creatorcontrib><description>Recent studies indicate that macrophages utilize NAD
+
-biosynthetic pathways to control inflammation and cell survival during the immune response and aging.</description><identifier>ISSN: 1529-2908</identifier><identifier>EISSN: 1529-2916</identifier><identifier>DOI: 10.1038/s41590-019-0353-x</identifier><identifier>PMID: 30858621</identifier><language>eng</language><publisher>New York: Nature Publishing Group US</publisher><subject>631/250/2504/342 ; 631/80/642/333 ; Aging ; Aging (Biology) ; Biomedical and Life Sciences ; Biomedicine ; Biosynthetic Pathways ; Cell survival ; DNA Damage ; Gene expression ; Immune response ; Immunity (Physiology) ; Immunity, Innate ; Immunology ; Infectious Diseases ; Inflammation ; Innate immunity ; Macrophages ; Medical schools ; NAD ; News & Views ; news-and-views ; Niacinamide ; Nicotinamide adenine dinucleotide ; Purines ; Reactive Oxygen Species</subject><ispartof>Nature immunology, 2019-04, Vol.20 (4), p.380-382</ispartof><rights>Springer Nature America, Inc. 2019</rights><rights>COPYRIGHT 2019 Nature Publishing Group</rights><rights>2019© Springer Nature America, Inc. 2019</rights><rights>Springer Nature America, Inc. 2019.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c501t-f02adcd25c9aacb237e018acc6671e1b3339867169e38e781c577ff735fd168f3</citedby><cites>FETCH-LOGICAL-c501t-f02adcd25c9aacb237e018acc6671e1b3339867169e38e781c577ff735fd168f3</cites><orcidid>0000-0001-7208-3886</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785,27929,27930</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30858621$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Billingham, Leah K.</creatorcontrib><creatorcontrib>Chandel, Navdeep S.</creatorcontrib><title>NAD-biosynthetic pathways regulate innate immunity</title><title>Nature immunology</title><addtitle>Nat Immunol</addtitle><addtitle>Nat Immunol</addtitle><description>Recent studies indicate that macrophages utilize NAD
+
-biosynthetic pathways to control inflammation and cell survival during the immune response and aging.</description><subject>631/250/2504/342</subject><subject>631/80/642/333</subject><subject>Aging</subject><subject>Aging (Biology)</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Biosynthetic Pathways</subject><subject>Cell survival</subject><subject>DNA Damage</subject><subject>Gene expression</subject><subject>Immune response</subject><subject>Immunity (Physiology)</subject><subject>Immunity, Innate</subject><subject>Immunology</subject><subject>Infectious Diseases</subject><subject>Inflammation</subject><subject>Innate immunity</subject><subject>Macrophages</subject><subject>Medical schools</subject><subject>NAD</subject><subject>News & Views</subject><subject>news-and-views</subject><subject>Niacinamide</subject><subject>Nicotinamide adenine dinucleotide</subject><subject>Purines</subject><subject>Reactive Oxygen Species</subject><issn>1529-2908</issn><issn>1529-2916</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp9kUtvEzEUhS1ERUvhB7BBkdiUxRRfe_xaRqWFShVIPNaW47FTVzOeYHtE8u_rkJIqCJAX98r-zvU9Ogi9AnwOmMp3uQWmcINBNZgy2qyfoBNgRDVEAX-677E8Rs9zvsMYWsHbZ-iYYskkJ3CCyKf5-2YRxryJ5daVYGcrU25_mk2eJbecelPcLMT4qwzDFEPZvEBH3vTZvXyop-j71eW3i4_NzecP1xfzm8YyDKXxmJjOdoRZZYxdECocBmms5VyAgwWlVMnacuWodEKCZUJ4LyjzHXDp6Sk6281dpfHH5HLRQ8jW9b2JbpyyJqBwW42ytqJv_kDvxinFup0mrWAYC6DqvxQoRrhgdak9tTS90yH6sSRjt1_rORNKtIRwVqnzv1D1dG4IdozOh3p_IHh7IKhMceuyNFPO-vrrl0MWdqxNY87Jeb1KYTBpowHrbfJ6l7yuyett8npdNa8fzE2LwXV7xe-oK0B2QK5PcenSo_t_T70HLwe0eg</recordid><startdate>20190401</startdate><enddate>20190401</enddate><creator>Billingham, Leah K.</creator><creator>Chandel, Navdeep S.</creator><general>Nature Publishing Group US</general><general>Nature Publishing Group</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>ISR</scope><scope>3V.</scope><scope>7QP</scope><scope>7QR</scope><scope>7T5</scope><scope>7TK</scope><scope>7TM</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>RC3</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-7208-3886</orcidid></search><sort><creationdate>20190401</creationdate><title>NAD-biosynthetic pathways regulate innate immunity</title><author>Billingham, Leah K. ; Chandel, Navdeep S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c501t-f02adcd25c9aacb237e018acc6671e1b3339867169e38e781c577ff735fd168f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>631/250/2504/342</topic><topic>631/80/642/333</topic><topic>Aging</topic><topic>Aging (Biology)</topic><topic>Biomedical and Life Sciences</topic><topic>Biomedicine</topic><topic>Biosynthetic Pathways</topic><topic>Cell survival</topic><topic>DNA Damage</topic><topic>Gene expression</topic><topic>Immune response</topic><topic>Immunity (Physiology)</topic><topic>Immunity, Innate</topic><topic>Immunology</topic><topic>Infectious Diseases</topic><topic>Inflammation</topic><topic>Innate immunity</topic><topic>Macrophages</topic><topic>Medical schools</topic><topic>NAD</topic><topic>News & Views</topic><topic>news-and-views</topic><topic>Niacinamide</topic><topic>Nicotinamide adenine dinucleotide</topic><topic>Purines</topic><topic>Reactive Oxygen Species</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Billingham, Leah K.</creatorcontrib><creatorcontrib>Chandel, Navdeep S.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection (ProQuest)</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Nature immunology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Billingham, Leah K.</au><au>Chandel, Navdeep S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>NAD-biosynthetic pathways regulate innate immunity</atitle><jtitle>Nature immunology</jtitle><stitle>Nat Immunol</stitle><addtitle>Nat Immunol</addtitle><date>2019-04-01</date><risdate>2019</risdate><volume>20</volume><issue>4</issue><spage>380</spage><epage>382</epage><pages>380-382</pages><issn>1529-2908</issn><eissn>1529-2916</eissn><abstract>Recent studies indicate that macrophages utilize NAD
+
-biosynthetic pathways to control inflammation and cell survival during the immune response and aging.</abstract><cop>New York</cop><pub>Nature Publishing Group US</pub><pmid>30858621</pmid><doi>10.1038/s41590-019-0353-x</doi><tpages>3</tpages><orcidid>https://orcid.org/0000-0001-7208-3886</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1529-2908 |
| ispartof | Nature immunology, 2019-04, Vol.20 (4), p.380-382 |
| issn | 1529-2908 1529-2916 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2190491654 |
| source | MEDLINE; Nature; Alma/SFX Local Collection |
| subjects | 631/250/2504/342 631/80/642/333 Aging Aging (Biology) Biomedical and Life Sciences Biomedicine Biosynthetic Pathways Cell survival DNA Damage Gene expression Immune response Immunity (Physiology) Immunity, Innate Immunology Infectious Diseases Inflammation Innate immunity Macrophages Medical schools NAD News & Views news-and-views Niacinamide Nicotinamide adenine dinucleotide Purines Reactive Oxygen Species |
| title | NAD-biosynthetic pathways regulate innate immunity |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-13T10%3A05%3A07IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=NAD-biosynthetic%20pathways%20regulate%20innate%20immunity&rft.jtitle=Nature%20immunology&rft.au=Billingham,%20Leah%20K.&rft.date=2019-04-01&rft.volume=20&rft.issue=4&rft.spage=380&rft.epage=382&rft.pages=380-382&rft.issn=1529-2908&rft.eissn=1529-2916&rft_id=info:doi/10.1038/s41590-019-0353-x&rft_dat=%3Cgale_proqu%3EA579742265%3C/gale_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2195267533&rft_id=info:pmid/30858621&rft_galeid=A579742265&rfr_iscdi=true |