Lupeol inhibits LPS-induced neuroinflammation in cerebellar cultures and induces neuroprotection associated to the modulation of astrocyte response and expression of neurotrophic and inflammatory factors

In the central nervous system (CNS), neuroinflammation, especially that modulated by the cell response of astrocytes and microglia, is associated with damage to neurons in neurodegenerative disorders such as Parkinson's disease, Alzheimer's disease and, Multiple Sclerosis. Lupeol is a diet...

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Veröffentlicht in:International immunopharmacology 2019-05, Vol.70, p.302-312
Hauptverfasser: Oliveira-Junior, Markley Silva, Pereira, Erica Patricia, de Amorim, Vanessa Cristina Meira, Reis, Luã Tainã Costa, do Nascimento, Ravena Pereira, da Silva, Victor Diogenes Amaral, Costa, Silvia Lima
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