Case series of testicular adrenal rest tumours in boys with congenital adrenal hyperplasia: A single centre experience

Testicular adrenal rest tumours (TART) are aberrant adrenal tissue within the testes (1). Although benign, they can lead to obstruction of the seminiferous tubules and infertility in patients with congenital adrenal hyperplasia (CAH). We report six boys who developed TART, a complication of CAH. Dia...

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Veröffentlicht in:	Medical journal of Malaysia 2019-02, Vol.74 (1), p.92-93
Hauptverfasser:	Karen Leong, S W, Wu, L L
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal Hyperplasia, Congenital - complications Adrenal Hyperplasia, Congenital - diagnosis Adrenal Rest Tumor - diagnosis Adrenal Rest Tumor - diagnostic imaging Adrenal Rest Tumor - drug therapy Glucocorticoids - therapeutic use Humans Infant Infant, Newborn Male Testicular Neoplasms - diagnosis Testicular Neoplasms - diagnostic imaging Testicular Neoplasms - drug therapy Ultrasonography
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Zusammenfassung:	Testicular adrenal rest tumours (TART) are aberrant adrenal tissue within the testes (1). Although benign, they can lead to obstruction of the seminiferous tubules and infertility in patients with congenital adrenal hyperplasia (CAH). We report six boys who developed TART, a complication of CAH. Diagnosis was confirmed by ultrasound and testicular vein sampling of elevated 17-hydroxyprogesterone (17-OHP) levels. Glucocorticoids dosages were increased 1½-2 folds to suppress size of the aberrant adrenal tissues. Despite reductions in 17-OHP, the lesions remained unchanged. Three patients had testis-sparing surgery to excise the TART and to preserve normal testicular tissues.
ISSN:	0300-5283