Guanosine protects against Ca2+-induced mitochondrial dysfunction in rats

•Guanosine prevent mitochondrial dysfunction induced by calcium (Ca2+) misbalance.•Maintaining mitochondrial functionality and calcium homeostasis as one of the main targets of guanosine.•Guanosine increase oxidative phosphorylation as a compensatory mechanism to maintain mitochondrial energy homeos...

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Veröffentlicht in:	Biomedicine & pharmacotherapy 2019-03, Vol.111, p.1438-1446
Hauptverfasser:	Courtes, Aline Alves, de Carvalho, Nelson Rodrigues, Gonçalves, Débora Farina, Hartmann, Diane Duarte, da Rosa, Pamela Carvalho, Dobrachinski, Fernando, Franco, Jeferson Luis, de Souza, Diogo Onofre Gomes, Soares, Félix Alexandre Antunes
Format:	Artikel
Sprache:	eng
Schlagworte:	Calcium Guanine-based purine High-resolution respirometry Nucleoside
Online-Zugang:	Volltext
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