Enhancement of water solubility of poorly water-soluble drugs by new biocompatible N-acetyl amino acid N-alkyl cholinium-based ionic liquids

[Display omitted] The major challenge of the pharmaceutical industry is to find potential solvents for poorly water-soluble drug molecules. Ionic liquids (ILs) have attracted this industry as (co-) solvents due to their unique physicochemical and biological properties. Herein, a straightforward appr...

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Veröffentlicht in:	European journal of pharmaceutics and biopharmaceutics 2019-04, Vol.137, p.227-232
Hauptverfasser:	Jesus, Ana R., Soromenho, Mário R.C., Raposo, Luís R., Esperança, José M.S.S., Baptista, Pedro V., Fernandes, Alexandra R., Reis, Patrícia M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Bioavailability Cytotoxicity Drug Delivery Ionic Liquids
Online-Zugang:	Volltext
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