A One‐Pot Ring‐Opening/Ring‐Closure Sequence for the Synthesis of Polycyclic Spirooxindoles

One‐pot ring‐opening/ring‐closure process of combining methyleneindolinone with 3‐aminooxindole has been developed in this work. Novel polycyclic spirooxindoles were efficiently assembled under mild conditions in high yields (up to 95 %) with moderate to good diastereoselectivities (up to >95:5 d...

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Veröffentlicht in:Chemistry : a European journal 2019-03, Vol.25 (18), p.4673-4677
Hauptverfasser: Ren, Ji‐Wei, Zhao, Qing‐Lan, Xiao, Jun‐An, Xia, Peng‐Ju, Xiang, Hao‐Yue, Chen, Xiao‐Qing, Yang, Hua
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Sprache:eng
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