Exogenous hyaluronic acid and chondroitin sulfate crosslinking treatment for increasing the amount and stability of glycosaminoglycans in bioprosthetic heart valves

Glutaraldehyde (GLUT) crosslinked bioprosthetic heart valves (BHVs) might fail due to progressive degradation and calcification. GLUT cannot stabilize glycosaminoglycans (GAGs), which are important for BHVs’ life time. In this current study we developed a new BHVs preparation strategy using exogenou...

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Veröffentlicht in:	Journal of materials science. Materials in medicine 2019-03, Vol.30 (3), p.38-8, Article 38
Hauptverfasser:	Lei, Yang, Ning, Qinggong, Tang, Yuyang, Wang, Yunbing
Format:	Artikel
Sprache:	eng
Schlagworte:	Biocompatibility Biomaterials Biomedical Engineering and Bioengineering Biomedical materials Calcification Ceramics Chemistry and Materials Science Chondroitin sulfate Clinical Applications of Biomaterials Composites Crosslinking Glass Glutaraldehyde Glycosaminoglycans Heart valves Hyaluronic acid Hydroxyl groups Materials Science Natural Materials Polymer Sciences Polysaccharides Regenerative Medicine/Tissue Engineering Saccharides Sodium Structural stability Sulfates Surfaces and Interfaces Thin Films
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