Chlorpyrifos activates cell pyroptosis and increases susceptibility on oxidative stress-induced toxicity by miR-181/SIRT1/PGC-1α/Nrf2 signaling pathway in human neuroblastoma SH-SY5Y cells: Implication for association between chlorpyrifos and Parkinson's disease

The insecticide exposure has been linked to Parkinson's disease (PD). In the present study, we used a most widely used cell line in study of PD, the SH-SY5Y cells, to investigate mechanisms of chlorpyrifos (CPF) induced cell toxicity and the possible roles of cell pyroptosis and oxidative stres...

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Veröffentlicht in:	Environmental toxicology 2019-06, Vol.34 (6), p.699-707
Hauptverfasser:	Zhao, Meng-Wen, Yang, Pu, Zhao, Ling-Ling
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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