Is Early Reimplantation of the Duodenal–Jejunal Bypass Liner Viable?
The endoscopically implanted duodenal–jejunal bypass liner (DJBL) is an impermeable fluoropolymer device which prevents food making contact with the proximal intestine, thus inducing weight loss and improvement of type 2 diabetes mellitus (T2DM). However, weight and HbA1c levels generally increase p...
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| Veröffentlicht in: | Obesity surgery 2019-05, Vol.29 (5), p.1690-1693 |
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| creator | Leventi, Eleni Günthert, Sarah J. Stier, Christine Staikov, Plamen Stein, Jürgen Farrag, Karima |
| description | The endoscopically implanted duodenal–jejunal bypass liner (DJBL) is an impermeable fluoropolymer device which prevents food making contact with the proximal intestine, thus inducing weight loss and improvement of type 2 diabetes mellitus (T2DM). However, weight and HbA1c levels generally increase post explantation. This study investigated the safety and feasibility of early DJBL reimplantation in five patients with obesity whose glucose levels had relapsed post explantation, examining the effect of reimplantation on weight loss, BMI and T2DM management. All DJBL implantation and explantation procedures were performed without complications. Despite reduction of T2DM medications, reduction in body weight and HbA1c levels resumed after reimplantation. In conclusion, early reimplantation of DJBL appears feasible, safe and effective. |
| doi_str_mv | 10.1007/s11695-019-03758-y |
| format | Article |
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However, weight and HbA1c levels generally increase post explantation. This study investigated the safety and feasibility of early DJBL reimplantation in five patients with obesity whose glucose levels had relapsed post explantation, examining the effect of reimplantation on weight loss, BMI and T2DM management. All DJBL implantation and explantation procedures were performed without complications. Despite reduction of T2DM medications, reduction in body weight and HbA1c levels resumed after reimplantation. 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All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c375t-3e284f2ec0095df4a0e2a7d77e2bce2c5495a2e4501846c057e362b41da5a4ee3</citedby><cites>FETCH-LOGICAL-c375t-3e284f2ec0095df4a0e2a7d77e2bce2c5495a2e4501846c057e362b41da5a4ee3</cites><orcidid>0000-0003-3558-3341</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11695-019-03758-y$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s11695-019-03758-y$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30826914$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Leventi, Eleni</creatorcontrib><creatorcontrib>Günthert, Sarah J.</creatorcontrib><creatorcontrib>Stier, Christine</creatorcontrib><creatorcontrib>Staikov, Plamen</creatorcontrib><creatorcontrib>Stein, Jürgen</creatorcontrib><creatorcontrib>Farrag, Karima</creatorcontrib><title>Is Early Reimplantation of the Duodenal–Jejunal Bypass Liner Viable?</title><title>Obesity surgery</title><addtitle>OBES SURG</addtitle><addtitle>Obes Surg</addtitle><description>The endoscopically implanted duodenal–jejunal bypass liner (DJBL) is an impermeable fluoropolymer device which prevents food making contact with the proximal intestine, thus inducing weight loss and improvement of type 2 diabetes mellitus (T2DM). 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| subjects | Adult Bariatric Surgery - instrumentation Body Mass Index Brief Communication Device Removal Diabetes Diabetes Mellitus, Type 2 - surgery Duodenum - surgery Endoscopy, Gastrointestinal Feasibility Studies Female Gastrointestinal surgery Glucose Glycated Hemoglobin A - analysis Humans Jejunum - surgery Male Medicine Medicine & Public Health Middle Aged Obesity Prostheses and Implants Reoperation Retrospective Studies Surgery Surgical outcomes Transplants & implants Weight control |
| title | Is Early Reimplantation of the Duodenal–Jejunal Bypass Liner Viable? |
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