N-acetylcysteine attenuates PM2.5-induced apoptosis by ROS-mediated Nrf2 pathway in human embryonic stem cells

While the effects of fine particulate matter (PM2.5) on embryonic toxicity are widely accepted, its exact mechanisms have not yet been fully elucidated, which partially attribute to lack of ideal research model. Embryonic stem cells (ESCs) have the capacity to differentiate into all cell types of th...

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Veröffentlicht in:	The Science of the total environment 2019-05, Vol.666, p.713-720
Hauptverfasser:	Jin, Lifang, Ni, Jian, Tao, Yuan, Weng, Xinyi, Zhu, Yuling, Yan, Junyan, Hu, Baowei
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Human embryonic stem cells N-acetylcysteine Nrf2 pathway Oxidative stress PM2.5
Online-Zugang:	Volltext
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